Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | KCNN2 | Q9H2S1 | 4/20 | 0.38 |
| ▸ | KCNN3 | Q9UGI6 | 4/20 | 0.38 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | SLC18A2 | Q05940 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4463783 | 0.86 | MAOA (0.44) | MAOAMAOBSLC6A4KCNN2KCNN3 | |
| SCHEMBL4455973 | 0.81 | SLC6A4 (0.54) | SLC6A4 | |
| SCHEMBL10955829 | 0.77 | MAOA (0.50) | MAOAMAOBSLC6A4KCNN2KCNN3 | |
| SCHEMBL4473882 | 0.74 | SLC6A2 (0.50) | SLC6A4 | |
| SCHEMBL18256785 | 0.68 | SLC6A4 (0.40) | MAOAMAOBSLC6A4CYP3A4CYP2D6 | |
| SCHEMBL4452789 | 0.68 | PKM (0.50) | MAOAMAOBSLC6A4SLC18A2CYP3A4 | |
| SCHEMBL9424882 | 0.67 | MAOB (0.73) | MAOAMAOBSLC6A4ABCB1CYP3A4 | |
| SCHEMBL29516234 | 0.67 | HTR2C (0.43) | MAOAMAOBSLC6A4 | |
| SCHEMBL4319951 | 0.66 | CYP3A4 (0.46) | SLC6A4CYP3A4CYP2D6 | |
| SCHEMBL4319946 | 0.66 | CHRNA7 (0.47) | SLC6A4CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |