Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNN2 | Q9H2S1 | 3/20 | 0.37 |
| ▸ | KCNN3 | Q9UGI6 | 3/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465797 | 0.86 | MAOA (0.42) | MAOASLC6A4MAOBCYP3A4CYP2D6 | |
| SCHEMBL10955829 | 0.80 | MAOA (0.50) | MAOASLC6A4MAOBCYP3A4CYP2D6 | |
| SCHEMBL4469390 | 0.72 | SLC6A2 (0.53) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL18256785 | 0.70 | SLC6A4 (0.40) | MAOASLC6A4MAOBCYP3A4CYP2D6 | |
| SCHEMBL4452789 | 0.70 | PKM (0.50) | MAOASLC6A4MAOBCYP3A4CYP2D6 | |
| SCHEMBL9424882 | 0.69 | MAOB (0.73) | MAOASLC6A4MAOBCYP3A4RAD52 | |
| SCHEMBL29516234 | 0.69 | HTR2C (0.43) | MAOASLC6A4MAOBSLC6A2SLC6A3 | |
| SCHEMBL4328800 | 0.68 | SLC6A4 (0.38) | MAOASLC6A4MAOBCYP3A4CYP2D6 | |
| SCHEMBL4459145 | 0.68 | PKM (0.43) | MAOASLC6A4MAOBCYP3A4CYP2D6 | |
| SCHEMBL4462738 | 0.68 | MAOA (0.38) | MAOASLC6A4MAOBCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |