SCHEMBL4466653

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2131850	0.90	KDM4E (0.55)	ALDH1A1HPGDKDM4ECYP1A2CYP2C9
	SCHEMBL4470392	0.80	NPC1 (0.52)	ALDH1A1HPGDKDM4ECYP1A2CYP2C9
	SCHEMBL2131853	0.80	XDH (0.55)	ALDH1A1HPGDKDM4ECYP1A2CYP2C9
	SCHEMBL4825992	0.80	CYP3A4 (0.54)	ALDH1A1HPGDKDM4ECYP1A2CYP2C9
	SCHEMBL9529962	0.80	CYP3A4 (0.54)	ALDH1A1HPGDKDM4ECYP1A2CYP2C9
	SCHEMBL28021757	0.78	LMNA (0.57)	ALDH1A1HPGDKDM4ECYP1A2CYP2C9
	SCHEMBL2133843	0.78	MAOB (0.59)	FAAHNR4A2MAOAMAOB
	SCHEMBL2132114	0.78	FFAR1 (0.45)	ALDH1A1HPGDKDM4ECYP1A2CYP2C9
	SCHEMBL4826512	0.77	EGLN1 (0.53)	ALDH1A1HPGDKDM4ECYP1A2CYP2C9
	SCHEMBL5579690	0.77	CHEK2 (0.59)	ALDH1A1HPGDKDM4ECYP1A2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.