Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PGD | P52209 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4467097 | 1.00 | LMNA (0.34) | LMNASMN1; SMN2MMP12SLC22A6TDP1 | |
| SCHEMBL9234611 | 0.87 | SMN1; SMN2 (0.38) | LMNASMN1; SMN2MMP12SLC22A6TDP1 | |
| SCHEMBL11853224 | 0.83 | LMNA (0.36) | LMNASMN1; SMN2SLC22A6TDP1 | |
| SCHEMBL1060755 | 0.79 | — | — | |
| SCHEMBL28479927 | 0.78 | MGAM (0.38) | LMNATDP1 | |
| SCHEMBL28479929 | 0.78 | MGAM (0.38) | LMNATDP1 | |
| SCHEMBL4474902 | 0.78 | — | — | |
| SCHEMBL29130335 | 0.77 | ENPEP (0.31) | — | |
| SCHEMBL27617039 | 0.74 | MGAM (0.38) | LMNASMN1; SMN2TDP1 | |
| SCHEMBL23573748 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605286-B2 | Hydroxy-protecting reagent and method of protecting hydroxy with the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-10-20 | — | — | US | disclosed |
| US-20070155983-A1 | Hydroxy-protecting reagent and method of protecting hydroxy with the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-07-05 | — | — | US | disclosed |
| EP-1652832-A1 | HYDROXY-PROTECTING REAGENT AND METHOD OF PROTECTING HYDROXY WITH THE SAME | Sumitomo Chemical Company, Limited (JP) | 2006-05-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155983-A1 | Hydroxy-protecting reagent and method of protecting hydroxy with the same | HADH, GRHPR, HSD11B1 | LMNA 1311/4885SMN1; SMN2 4246/4885MMP12 3013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.