SCHEMBL4467348

SCHEMBL4467348

C=CCc1ccccc1-c1cccs1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.56
GABRA1 P14867 1/20 0.46
GABRB2 P47870 1/20 0.46
KDM4E B2RXH2 3/20 0.39
ALDH1A1 P00352 3/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 2/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.39
KMT2A Q03164 2/20 0.39
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.37
TP53 P04637 1/20 0.37
GLA P06280 1/20 0.37
GAA P10253 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
ALOX5 P09917 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6102540 0.84 ALOX5 (0.43) LTA4HGABRA1GABRB2KDM4EALDH1A1
SCHEMBL6028964 0.79 LTA4H (0.61) LTA4HKDM4EALDH1A1HPGDMEN1
SCHEMBL2362466 0.78 GABRA1 (0.61) GABRA1GABRB2KDM4EALDH1A1HPGD
SCHEMBL29900352 0.78 GABRA1 (0.61) GABRA1GABRB2KDM4EALDH1A1HPGD
SCHEMBL3906475 0.76 LTA4H (0.49) LTA4HKDM4EALDH1A1HPGDMEN1
SCHEMBL4846964 0.76 LTA4H (0.61) LTA4HKDM4EALDH1A1HPGDMEN1
SCHEMBL5023959 0.76 LTA4H (0.66) LTA4HKDM4EALDH1A1HSD17B10MEN1
SCHEMBL4845248 0.76 LTA4H (0.61) LTA4HKDM4EALDH1A1HPGDMEN1
SCHEMBL477614 0.76 LTA4H (0.61) LTA4HKDM4EALDH1A1HPGDHSD17B10
SCHEMBL3780733 0.76 LTA4H (0.61) LTA4HKDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103682151-A Photovoltaic cell module TOSHIBA KK 2014-03-26 CN disclosed
EP-1524289-B1 POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2009-09-16 EP disclosed
US-20070149639-A1 Polymerizable composition, optical material comprising the composition and method for producing the material HORIKOSHI HIROSHI 2007-06-28 US disclosed
EP-1524289-A1 POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2005-04-20 EP disclosed
US-20040254258-A1 Polymerizable composition, optical material comprising the composition and method for producing the material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2004-12-16 US disclosed
US-4816454-A CARDIOVASCULAR DISORDERS CASSELLA AKTIENGESELLSCHAFT (DE) 1989-03-28 US disclosed
EP-0175363-A2 4,5-Dihydro-3(2H)-pyridazinones, process for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1986-03-26 EP disclosed