SCHEMBL4469262

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14965792	0.84	ALPL (0.56)	ALPLCYP4F2CYP4A11NPC1RAB9A
	SCHEMBL4469748	0.82	HCAR2 (0.50)	ALPLDRD4DRD2DRD3CCNA2
	SCHEMBL4260262	0.78	CYP4F2 (0.52)	ALPLCYP4F2CYP4A11NPC1RAB9A
	SCHEMBL1788615	0.75	CYP4F2 (0.57)	CYP4F2CYP4A11RAB9AMEN1KMT2A
	SCHEMBL19100014	0.73	HCAR2 (0.59)	IGF1RNPC1RAB9AMAPTL3MBTL1
	SCHEMBL3346932	0.73	USP30 (0.47)	ALPLDRD4DRD2DRD3CCNA2
	SCHEMBL4255413	0.72	JMJD6 (0.55)	ALPLCYP4F2CYP4A11NPC1RAB9A
	SCHEMBL4503741	0.72	CYP4F2 (0.60)	CYP4F2CYP4A11PTGDRKMT2AKDM4E
	SCHEMBL4462430	0.72	P2RX7 (0.56)	ALPLNPC1RAB9AMAPTL3MBTL1
	SCHEMBL4470984	0.72	P2RX7 (0.75)	P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.