SCHEMBL4469748

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4469262	0.82	ALPL (0.51)	DRD4CCNA2CDK2CCNA1DRD2
	SCHEMBL17948808	0.80	CCNA2 (0.60)	HCAR2DRD4CCNA2CDK2CCNA1
	SCHEMBL4471895	0.79	P2RX7 (0.57)	HCAR2XDHTDP1GRIK1GRIA1
	SCHEMBL4470990	0.78	CCNA2 (0.44)	DRD4CCNA2CDK2CCNA1DRD2
	SCHEMBL19805568	0.76	DRD4 (0.76)	DRD4DRD2DRD3MKNK1MKNK2
	SCHEMBL4470984	0.76	P2RX7 (0.75)	—
	SCHEMBL3346932	0.75	USP30 (0.47)	HCAR2DRD4CCNA2CDK2CCNA1
	SCHEMBL20278952	0.74	CCNA2 (0.48)	HCAR2DRD4CCNA2CDK2CCNA1
	SCHEMBL14686771	0.73	DRD4 (0.69)	DRD4DRD2DRD3TDP1CA12
	SCHEMBL2374222	0.73	DRD4 (0.67)	HCAR2DRD4DRD2DRD3MKNK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.