SCHEMBL4471895

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3346686	0.88	P2RX7 (0.57)	P2RX7L3MBTL1ALPLCA9NPC1
	SCHEMBL4462430	0.85	P2RX7 (0.56)	P2RX7L3MBTL1ALPLNPC1RAB9A
	SCHEMBL14966653	0.83	P2RX7 (0.64)	P2RX7L3MBTL1ALPLNPC1RAB9A
	SCHEMBL14965792	0.82	ALPL (0.56)	P2RX7L3MBTL1ALPLNPC1RAB9A
	SCHEMBL4469748	0.79	HCAR2 (0.50)	XDHALPLGRIK1GRIA1GRIA2
	SCHEMBL4256795	0.76	XDH (0.52)	L3MBTL1XDHALPLNPC1RAB9A
	SCHEMBL3346696	0.75	NPC1 (0.53)	P2RX7L3MBTL1NPC1RAB9ASMN1; SMN2
	SCHEMBL2771204	0.75	ALDH1A1 (0.68)	XDHNPC1RAB9ASMN1; SMN2GRIK1
	SCHEMBL3342192	0.75	ALPL (0.49)	P2RX7L3MBTL1ALPLCA9NPC1
	SCHEMBL4472392	0.75	XDH (0.58)	XDHGRIK1GRIA1GRIA2GRIA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.