Xanthoxylin

Xanthoxylin

SCHEMBL44708

COc1cc(O)c(C(C)=O)c(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 8/20 1.00
USP2 O75604 2/20 1.00
MAPK1 P28482 2/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
ABCG2 Q9UNQ0 5/20 0.62
MAPT P10636 4/20 0.58
KDM4E B2RXH2 3/20 0.58
ABL1 P00519 1/20 0.58
POLB P06746 1/20 0.58
RECQL P46063 1/20 0.58
RIN1 Q13671 1/20 0.58
CTDSP1 Q9GZU7 1/20 0.58
CYP2D6 P10635 1/20 0.56
CYP2C19 P33261 1/20 0.56
KMT2A Q03164 5/20 0.55
NFKB1 P19838 1/20 0.55
DPP4 P27487 1/20 0.55
NFKB2 Q00653 1/20 0.55
RELA Q04206 1/20 0.55
TP53 P04637 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xanthoxylin SCHEMBL29349586 1.00 CYP3A4 (1.00) CYP3A4USP2MAPK1SMN1; SMN2ABCG2
Xanthoxylin SCHEMBL28802531 0.98 CYP3A4 (0.96) CYP3A4USP2MAPK1SMN1; SMN2ABCG2
Xanthoxylin SCHEMBL28776222 0.90 CYP3A4 (0.81) CYP3A4USP2MAPK1SMN1; SMN2ABCG2
Xanthoxylin SCHEMBL28853290 0.89 CYP3A4 (0.79) CYP3A4USP2MAPK1SMN1; SMN2ABCG2
SCHEMBL2811810 0.88 CYP3A4 (0.78) CYP3A4USP2MAPK1SMN1; SMN2ABCG2
SCHEMBL2029772 0.88 CYP3A4 (0.78) CYP3A4USP2MAPK1SMN1; SMN2ABCG2
SCHEMBL29757572 0.86 CYP3A4 (0.76) CYP3A4USP2MAPK1SMN1; SMN2ABCG2
SCHEMBL28370780 0.86 CYP3A4 (0.76) CYP3A4USP2MAPK1SMN1; SMN2ABCG2
SCHEMBL1937218 0.86 CYP3A4 (0.76) CYP3A4USP2MAPK1SMN1; SMN2ABCG2
SCHEMBL1614609 0.85 CYP3A4 (0.73) CYP3A4USP2MAPK1SMN1; SMN2ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1046 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122074487-A Application of Zanthoxylum bungeanum extract in preparation of plant weeding products and plant herbicide 2026-05-26 CN claimed
CN-121350361-B Big data-based intelligent adaptation method and system for flavor of hotpot condiment 四川远方云天食品科技有限公司 2026-05-15 CN claimed
CN-122030430-A Preparation and application methods of high-efficiency nontoxic insecticidal bactericidal nutrient solution biopesticide 北京仙童琼浆科技有限公司 2026-05-15 CN claimed
US-20260096569-A1 EDIBLE COATING WITH ANTIMICROBIAL PROPERTIES APEEL TECH INC (US) 2026-04-09 US claimed
US-12495797-B2 Insect repellent RILIS CO., LTD. (JP) 2025-12-16 US claimed
US-20250368926-A1 CLEANING WET WIPE DAIO PAPER CORPORATION (JP) 2025-12-04 US claimed
EP-4544907-A1 CLEANING WET WIPE Daio Paper Corporation (JP) 2025-04-30 EP claimed
CN-119896655-A Application of Zanthoxylum bungeanum extract in preparation of products for treating spermatogenic disorder 黄淮学院 2025-04-29 CN claimed
CN-119899168-A Separation and application of brevifolin in sheep opening 广西壮族自治区中国科学院广西植物研究所 2025-04-29 CN claimed
CN-119857061-A Integrated nanoparticle for sun protection and repair as well as preparation method and application thereof 四川大学华西医院 2025-04-22 CN claimed
CN-101278930-A New purpose of brevifolin UNIV TSINGHUA (CN) 2008-10-08 CN claimed
CN-101278897-A Process for preparing brevifolin solid lipid nano particle UNIV XI AN JIAOTONG (CN) 2008-10-08 CN claimed
WO-2008031940-A2 XANTHOXYLINE-BASED COMPOSITION AND COSMETIC USE THEREOF PIERRE FABRE DERMO-COSMETIQUE (FR) 2008-03-20 WO claimed
CN-100360115-C Molecular coating method of plant polyphenol kind substance XIE JUN (CN) 2008-01-09 CN claimed
CN-1823730-A Molecular coating method of plant polyphenol kind substance XIE JUN (CN) 2006-08-30 CN claimed
CN-1824631-A Molecular modification method of active fat soluble plant polyphenol kind substance XIE JUN (CN) 2006-08-30 CN claimed
US-20050271608-A1 Skin whitening compositions based on hydroxyaryl alkyl ketones and their isosteric derivatives GUPTA SHYAM K 2005-12-08 US claimed
US-20030078231-A1 Orthomolecular sulpho-adenosylmethionine derivatives with antioxidant properties WILBURN MICHAEL D (US) 2003-04-24 US claimed
US-20030007961-A1 Orthomolecular vitamin E derivatives WILBURN MICHAEL D (US) 2003-01-09 US claimed
CN-1123030-A Inclusion complexes of taxol or taxotere or taxus extract formed with cyclodextrins, its preparation and use CHINOIN GYOGYSZER ES VEGYESZET (HU) 1996-05-22 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030078231-A1 Orthomolecular sulpho-adenosylmethionine derivatives with antioxidant properties MAT1A, LPO, TPMT CYP3A4 2763/4885USP2 1678/4885MAPK1 2079/4885
US-20030007961-A1 Orthomolecular vitamin E derivatives RBP4, RBP1, VDR CYP3A4 2879/4885USP2 3531/4885MAPK1 2342/4885
US-20260096569-A1 EDIBLE COATING WITH ANTIMICROBIAL PROPERTIES CYP51A1, ERG28, NISCH CYP3A4 3888/4885USP2 1858/4885MAPK1 673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.