Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4470905 | 1.00 | ALDH1A1 (0.35) | ALDH1A1CCR2CMA1TRPV1MAOB | |
| SCHEMBL4493278 | 0.91 | RAB9A (0.38) | ALDH1A1RAB9AL3MBTL1HPGDKDM4E | |
| SCHEMBL4493283 | 0.91 | RAB9A (0.38) | ALDH1A1RAB9AL3MBTL1HPGDKDM4E | |
| SCHEMBL4478365 | 0.87 | ALDH1A1 (0.39) | ALDH1A1CMA1MAOBTSHRL3MBTL1 | |
| SCHEMBL4478374 | 0.87 | ALDH1A1 (0.39) | ALDH1A1CMA1MAOBTSHRL3MBTL1 | |
| SCHEMBL4482617 | 0.87 | POLB (0.39) | ALDH1A1CMA1HPGDKDM4EPOLB | |
| SCHEMBL4482624 | 0.87 | POLB (0.39) | ALDH1A1CMA1HPGDKDM4EPOLB | |
| SCHEMBL4486658 | 0.81 | CCR2 (0.33) | CCR2CMA1TRPV1HPGD | |
| SCHEMBL4486655 | 0.81 | CCR2 (0.33) | CCR2CMA1TRPV1HPGD | |
| SCHEMBL4471445 | 0.81 | ALDH1A1 (0.38) | ALDH1A1CMA1MAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582651-B2 | Pyrrolopyridine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-01 | — | — | US | disclosed |
| US-20060167038-A1 | Pyrrolopyridine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1535922-A1 | PYRROLOPYRIDINE DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2005-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167038-A1 | Pyrrolopyridine derivative and use thereof | OPRD1, TRPV1, OPRM1 | ALDH1A1 1363/4885CCR2 125/4885CMA1 2104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.