Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | EBP | Q15125 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4468905 | 0.85 | POLB (0.53) | MEN1KMT2ASIGMAR1GRIN2DGRIN3B | |
| SCHEMBL512500 | 0.73 | GAA (0.64) | MEN1KMT2AALOX15TSHRPOLB | |
| SCHEMBL4471232 | 0.72 | KMT2A (0.67) | MEN1KMT2APOLBUSP2TDP1 | |
| SCHEMBL14218483 | 0.72 | ALDH1A1 (0.80) | MEN1KMT2ATSHRPOLBUSP2 | |
| SCHEMBL9879486 | 0.70 | KMT2A (1.00) | MEN1KMT2ATSHRPOLBUSP2 | |
| SCHEMBL9227594 | 0.69 | SIGMAR1 (0.70) | MEN1KMT2ASIGMAR1GRIN2DGRIN3B | |
| Ditolylguanidine SCHEMBL80339 | 0.69 | SIGMAR1 (1.00) | MEN1KMT2ASIGMAR1GRIN2DGRIN3B | |
| Ditolylguanidine SCHEMBL29364709 | 0.69 | SIGMAR1 (1.00) | MEN1KMT2ASIGMAR1GRIN2DGRIN3B | |
| Ditolylguanidine SCHEMBL3388414 | 0.69 | SIGMAR1 (1.00) | MEN1KMT2ASIGMAR1GRIN2DGRIN3B | |
| Ditolylguanidine SCHEMBL158674 | 0.69 | SIGMAR1 (1.00) | MEN1KMT2ASIGMAR1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504502-B2 | Guanidinopyrimidinone compounds and phase change inks containing same | XEROX CORPORATION (US) | 2009-03-17 | — | — | US | disclosed |
| US-20080171877-A1 | GUANIDINOPYRIMIDINONE COMPOUNDS AND PHASE CHANGE INKS CONTAINING SAME | XEROX CORPORATION (US) | 2008-07-17 | — | — | US | disclosed |
| US-7371858-B2 | Guanidinopyrimidinone compounds and phase change inks containing same | XEROX CORPORATION (US) | 2008-05-13 | — | — | US | disclosed |
| US-20060149063-A1 | Guanidinopyrimidinone compounds and phase change inks containing same | XEROX CORPORATION | 2006-07-06 | — | — | US | disclosed |
| US-6811595-B2 | Guanidinopyrimidinone compounds and phase change inks containing same | XEROX CORPORATION | 2004-11-02 | — | — | US | disclosed |
| US-20040060474-A1 | Guanidinopyrimidinone compounds and phase change inks containing same | XEROX CORPORATION | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060149063-A1 | Guanidinopyrimidinone compounds and phase change inks containing same | RPP30, INO80, CDK20 | MEN1 4220/4885KMT2A 2305/4885SIGMAR1 40/4885 |
| US-20040060474-A1 | Guanidinopyrimidinone compounds and phase change inks containing same | CCNI, INO80, CCNY | MEN1 4310/4885KMT2A 1779/4885SIGMAR1 55/4885 |
| US-20080171877-A1 | GUANIDINOPYRIMIDINONE COMPOUNDS AND PHASE CHANGE INKS CONTAINING SAME | INO80, RPP30, RO60 | MEN1 4021/4885KMT2A 1968/4885SIGMAR1 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.