Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 13/20 | 0.79 |
| ▸ | PGR | P06401 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | ACP1 | P24666 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487941 | 0.91 | FBP1 (0.79) | FBP1PGRMEN1KMT2AMAPT | |
| SCHEMBL6295746 | 0.86 | CA12 (0.69) | FBP1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL4196236 | 0.84 | LMNA (0.78) | FBP1LMNAMAPTACP1CA12 | |
| SCHEMBL5186566 | 0.83 | LMNA (0.72) | FBP1LMNAMEN1KMT2AMAPT | |
| SCHEMBL9529388 | 0.83 | LMNA (0.63) | FBP1LMNAMEN1KMT2AMAPT | |
| SCHEMBL6301527 | 0.81 | MAPT (0.58) | FBP1LMNAMEN1KMT2AMAPT | |
| SCHEMBL19630984 | 0.80 | FBP1 (0.68) | FBP1PGR | |
| SCHEMBL4476659 | 0.79 | KMT2A (0.63) | FBP1LMNAMEN1KMT2AMAPT | |
| SCHEMBL5184894 | 0.79 | LMNA (0.70) | FBP1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL9486922 | 0.79 | FBP1 (0.61) | FBP1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067607-A2 | COMBINATIONS OF PDE4 INHIBITORS AND ANTIPSYCHOTICS FOR THE TREATMENT OF PSYCHOTIC DISORDERS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2009-05-28 | — | — | WO | disclosed |