SCHEMBL447235

SCHEMBL447235

CC(O)COC(=O)C(C)O

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.47
MAPK1 P28482 1/20 0.40
TSHR P16473 5/20 0.39
HSD17B10 Q99714 1/20 0.39
TP53 P04637 1/20 0.38
TDP1 Q9NUW8 2/20 0.33
LMNA P02545 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24414494 1.00 MAPT (0.47) MAPTMAPK1TSHRHSD17B10TP53
SCHEMBL24414506 1.00 MAPT (0.47) MAPTMAPK1TSHRHSD17B10TP53
SCHEMBL24414476 1.00 MAPT (0.47) MAPTMAPK1TSHRHSD17B10TP53
SCHEMBL24414470 1.00 MAPT (0.47) MAPTMAPK1TSHRHSD17B10TP53
SCHEMBL24414542 1.00 MAPT (0.47) MAPTMAPK1TSHRHSD17B10TP53
SCHEMBL4733112 0.84 MAPT (0.40) MAPTMAPK1TSHRHSD17B10TP53
SCHEMBL536618 0.84 TDP1 (0.48) MAPTMAPK1TSHRHSD17B10TP53
SCHEMBL6215006 0.83 TSHR (0.50) MAPTMAPK1TSHRHSD17B10TP53
SCHEMBL767015 0.83 TSHR (0.50) MAPTMAPK1TSHRHSD17B10TP53
SCHEMBL1498188 0.83 MAPT (0.47) MAPTMAPK1TSHRHSD17B10TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 476 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12338197-B2 Process for preparation of amides and esters of 2-((2-hydroxypropanoyl)oxy)propanoic acid UNIVERZITA PARDUBICE (CZ) 2025-06-24 US claimed
EP-4361238-A1 COMPOSITIONS COMPRISING GLYCAMINES ChemTEK UG (haftungsbeschränkt) (DE) 2024-05-01 EP claimed
US-20230118459-A1 ANTIVIRAL TREATMENT ECOSYNTH NV (BE) 2023-04-20 US claimed
EP-4114376-A1 ANTIVIRAL TREATMENT Ecosynth (BE) 2023-01-11 EP claimed
US-20220041542-A1 A process for preparation of amides and esters of 2-((2-hydroxypropanoyl)oxy)propanoic acid UNIVERZITA PARDUBICE (CZ) 2022-02-10 US claimed
EP-3898570-A1 A PROCESS FOR PREPARATION OF AMIDES AND ESTHERS OF 2-((2-HYDROXYPANOYL)OXY)PROPANOIC ACID Univerzita Pardubice (CZ) 2021-10-27 EP claimed
CN-105030555-B Surfactant compositions and high oil content formulations containing the same 赢创运营有限公司 2021-10-15 CN claimed
WO-2021176010-A1 ANTIVIRAL TREATMENT ECOSYNTH NV (BE) 2021-09-10 WO claimed
CN-111920725-A Children shampoo and shower gel containing organic acid mild preservative and preparation method thereof 福建省梦娇兰日用化学品有限公司 2020-11-13 CN claimed
WO-2020125823-A1 A PROCESS FOR PREPARATION OF AMIDES AND ESTHERS OF 2-((2-HYDROXYPANOYL)OXY)PROPANOIC ACID UNIVERZITA PARDUBICE (CZ) 2020-06-25 WO claimed
US-20020197185-A1 ANTIMICROBIAL COATINGS FOR MEDICAL DEVICES ETHICON, INC. 2002-12-26 US claimed
EP-1009398-A1 MOLECULAR COMPLEX AND CONTROL-RELEASE OF ALPHA HYDROXYACIDS Yu, Ruey J., Dr. (US) 2000-06-21 EP claimed
US-5886041-A SKIN DISORDERS TRISTRATA TECHNOLOGY, INC. (US) 1999-03-23 US claimed
US-5877212-A HYDROGEN BONDING WITH COMPLEXING AGENT YU RUEY J (US) 1999-03-02 US claimed
WO-1998046217-A1 MOLECULAR COMPLEX AND CONTROL-RELEASE OF ALPHA HYDROXYACIDS YU RUEY J (US) 1998-10-22 WO claimed
US-5811112-A LEAVE-ON SKIN CARE PRODUCT; TREATMENT OF DRYNESS, WRINKLING CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO INC. (US) 1998-09-22 US claimed
EP-0413528-B1 Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use YU RUEY J (US) 1995-11-15 EP claimed
EP-0671162-A2 Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use Yu, Ruey J., Dr. (US) 1995-09-13 EP claimed
US-5091171-A Skin disorders IGI, INC. 1992-02-25 US claimed
EP-0413528-A1 Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use Yu, Ruey J., Dr. (US) 1991-02-20 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230118459-A1 ANTIVIRAL TREATMENT MAVS, ACE, ACE2 MAPT 2171/4885MAPK1 4086/4885TSHR 4316/4885
US-20220041542-A1 A process for preparation of amides and esters of 2-((2-hydroxypropanoyl)oxy)propanoic acid ADH1C, ADH1A, ADH5 MAPT 3867/4885MAPK1 2888/4885TSHR 540/4885
US-12338197-B2 Process for preparation of amides and esters of 2-((2-hydroxypropanoyl)oxy)propanoic acid HRH2, LDHA, HCAR2 MAPT 3861/4885MAPK1 2557/4885TSHR 69/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.