SCHEMBL4472446

SCHEMBL4472446

CC1(C)CC2(CC(C)(C)c3cc(CCOCCOc4ccccc4)c(O)cc32)c2cc(O)c(CCOCCOc3ccccc3)cc21

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPK1 P28482 2/20 0.35
KDM4E B2RXH2 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
PPARG P37231 1/20 0.34
PKM P14618 2/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
MAOA P21397 2/20 0.33
LMNA P02545 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TP53 P04637 1/20 0.33
POLB P06746 1/20 0.33
PARP10 Q53GL7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4471742 0.86 L3MBTL1 (0.39) MAOBALDH1A1MAPK1KDM4ETDP1
SCHEMBL4471806 0.83
SCHEMBL4463972 0.83 POLB (0.31) POLB
SCHEMBL4474208 0.82 ALDH1A1 (0.38) MAOBALDH1A1MAPK1TDP1PPARG
SCHEMBL4459389 0.80 TSHR (0.35) ALDH1A1TDP1MAPTTP53
SCHEMBL4464086 0.77 POLB (0.34) POLB
SCHEMBL4472452 0.76 PPARG (0.36) MAOBALDH1A1MAPK1PPARGPKM
SCHEMBL4471829 0.75 TYR (0.36) ALDH1A1TDP1MAPTTP53
SCHEMBL4471749 0.74 PPARG (0.35) MAOBMAPK1PPARGPKMMAPT
SCHEMBL4474017 0.73 ESR1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed
US-6028161-A EXCELLENT TRANSPARENCY, HEAT RESISTANCE AND MECHANICAL PROPERTIES AND A LOW BIREFRINGENCE, MELT FLUIDITY AND MOLDABILITY; AN OPTICAL DISK, LENS AND AN OPTICAL FIBER MITSUI CHEMICALS, INC. (JP) 2000-02-22 US disclosed
EP-0926180-A2 A polycarbonate copolymer and applications thereof Mitsui Chemicals, Inc. (JP) 1999-06-30 EP disclosed