SCHEMBL4471749

SCHEMBL4471749

CC(OCCOc1ccccc1)Oc1cc2c(cc1O)C1(CC2(C)C)CC(C)(C)c2cc(OC(C)OCCOc3ccccc3)c(O)cc21

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.35
NPSR1 Q6W5P4 1/20 0.34
PARP10 Q53GL7 1/20 0.33
MAPT P10636 2/20 0.32
PKM P14618 2/20 0.32
RAB9A P51151 1/20 0.32
MAOB P27338 3/20 0.32
LMNA P02545 3/20 0.32
MAOA P21397 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
MAPK1 P28482 1/20 0.31
PTGER4 P35408 1/20 0.31
PTGER2 P43116 1/20 0.31
HPGD P15428 1/20 0.31
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4474208 0.86 ALDH1A1 (0.38) PPARGPARP10MAPTPKMRAB9A
SCHEMBL4462233 0.84 OPRM1 (0.30)
SCHEMBL4471742 0.83 L3MBTL1 (0.39) PPARGMAPTPKMRAB9AMAOB
SCHEMBL4472452 0.82 PPARG (0.36) PPARGPARP10MAPTPKMRAB9A
SCHEMBL4467223 0.82
SCHEMBL4472446 0.74 MAOB (0.36) PPARGPARP10MAPTPKMRAB9A
SCHEMBL4460699 0.74 KCNH2 (0.30)
SCHEMBL4455722 0.71 OPRM1 (0.42)
SCHEMBL4474023 0.69 RXRA (0.41) PPARG
SCHEMBL8019962 0.69 HNF4A (0.41) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed
US-6028161-A EXCELLENT TRANSPARENCY, HEAT RESISTANCE AND MECHANICAL PROPERTIES AND A LOW BIREFRINGENCE, MELT FLUIDITY AND MOLDABILITY; AN OPTICAL DISK, LENS AND AN OPTICAL FIBER MITSUI CHEMICALS, INC. (JP) 2000-02-22 US disclosed
EP-0926180-A2 A polycarbonate copolymer and applications thereof Mitsui Chemicals, Inc. (JP) 1999-06-30 EP disclosed