SCHEMBL4472452

SCHEMBL4472452

CC(OCCOc1ccccc1)c1cc2c(cc1O)C1(CC2(C)C)CC(C)(C)c2cc(C(C)OCCOc3ccccc3)c(O)cc21

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.36
LMNA P02545 2/20 0.34
MAPK1 P28482 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PKM P14618 2/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
MAOB P27338 3/20 0.33
MAOA P21397 2/20 0.33
PARP10 Q53GL7 1/20 0.32
PTGER4 P35408 1/20 0.32
PTGER2 P43116 1/20 0.32
NPC1 O15118 1/20 0.32
POLB P06746 1/20 0.32
CASP6 P55212 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4463981 0.83
SCHEMBL4471749 0.82 PPARG (0.35) PPARGLMNAMAPK1L3MBTL1PKM
SCHEMBL4471809 0.81
SCHEMBL4474208 0.81 ALDH1A1 (0.38) PPARGLMNAMAPK1L3MBTL1PKM
SCHEMBL4471742 0.78 L3MBTL1 (0.39) PPARGLMNAMAPK1L3MBTL1PKM
SCHEMBL4472446 0.76 MAOB (0.36) PPARGLMNAMAPK1L3MBTL1PKM
SCHEMBL4467213 0.71 LMNA (0.38) LMNAMAPK1PKMMAPTMEN1
SCHEMBL18656390 0.67 RXRA (0.33) MEN1KMT2A
SCHEMBL16021623 0.67 RXRA (0.33) MEN1KMT2A
SCHEMBL196263 0.66 RXRA (0.35) MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed
US-6028161-A EXCELLENT TRANSPARENCY, HEAT RESISTANCE AND MECHANICAL PROPERTIES AND A LOW BIREFRINGENCE, MELT FLUIDITY AND MOLDABILITY; AN OPTICAL DISK, LENS AND AN OPTICAL FIBER MITSUI CHEMICALS, INC. (JP) 2000-02-22 US disclosed
EP-0926180-A2 A polycarbonate copolymer and applications thereof Mitsui Chemicals, Inc. (JP) 1999-06-30 EP disclosed