Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 1/20 | 0.45 |
| ▸ | PNP | P00491 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829370 | 0.80 | POLB (0.50) | DPYDPNPPOLBSMN1; SMN2MEN1 | |
| SCHEMBL3573556 | 0.80 | DPYD (0.48) | DPYDPNPMAPK14POLBSMN1; SMN2 | |
| SCHEMBL6652475 | 0.72 | DPYD (0.41) | DPYDPNPPOLBSMN1; SMN2PPARG | |
| SCHEMBL6472836 | 0.72 | NR4A1 (0.47) | DPYDPNPSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6472152 | 0.71 | MAOB (0.47) | DPYDPNPPOLBSMN1; SMN2GAA | |
| SCHEMBL6472151 | 0.70 | PARP10 (0.49) | DPYDPNP | |
| SCHEMBL3653544 | 0.69 | PNP (0.44) | DPYDPNPPOLBHPGD | |
| SCHEMBL6471640 | 0.69 | DPYD (0.41) | DPYDPNPMAPK14POLBSMN1; SMN2 | |
| SCHEMBL6472682 | 0.69 | LMNA (0.49) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL6647198 | 0.68 | PNP (0.40) | DPYDPNPPOLBSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629363-B2 | antiinflammatory agent for treating asthma and chronic pulmonary inflammatory disease | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |