Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.49 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | DPYD | Q12882 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472836 | 0.91 | NR4A1 (0.47) | PNPDPYDHDAC1HDAC6 | |
| SCHEMBL6471484 | 0.89 | DPYD (0.46) | PARP10PARP15PARP14DPYDKDM4E | |
| SCHEMBL6647198 | 0.88 | PNP (0.40) | PARP10PLA2G10PLA2G2APNPDPYD | |
| SCHEMBL6472682 | 0.87 | LMNA (0.49) | HDAC1HDAC6 | |
| SCHEMBL6652475 | 0.86 | DPYD (0.41) | PNPDPYDHDAC1HDAC6 | |
| SCHEMBL6473794 | 0.85 | SIRT2 (0.40) | PARP10PLA2G2APARP1PNPDPYD | |
| SCHEMBL6472152 | 0.81 | MAOB (0.47) | PNPDPYDMAOB | |
| SCHEMBL6471640 | 0.80 | DPYD (0.41) | PLA2G2APNPDPYDKDM4EMAOB | |
| SCHEMBL6471088 | 0.80 | THRA (0.45) | DPYD | |
| SCHEMBL6652195 | 0.78 | MAPK14 (0.38) | PNPDPYDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |