Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 5/20 | 0.45 |
| ▸ | RXRB | P28702 | 4/20 | 0.45 |
| ▸ | RXRG | P48443 | 2/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | DPYD | Q12882 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472151 | 0.91 | PARP10 (0.49) | DPYDPNPHDAC1HDAC6 | |
| SCHEMBL6472682 | 0.89 | LMNA (0.49) | TSHRSMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL6652475 | 0.88 | DPYD (0.41) | RXRARXRBRXRGPTGER1PTGER4 | |
| SCHEMBL6647198 | 0.86 | PNP (0.40) | SMN1; SMN2HPGDDPYDPNPHDAC1 | |
| SCHEMBL6472152 | 0.83 | MAOB (0.47) | SMN1; SMN2DPYDPNP | |
| SCHEMBL6648876 | 0.82 | RXRA (0.48) | NR4A1NR4A2NR4A3RXRARXRB | |
| SCHEMBL6471484 | 0.82 | DPYD (0.46) | NR4A2PTGER1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6471088 | 0.82 | THRA (0.45) | PTGER1PTGER4PTGER3PTGER2TSHR | |
| SCHEMBL6473794 | 0.81 | SIRT2 (0.40) | TSHRSMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL6652195 | 0.80 | MAPK14 (0.38) | SMN1; SMN2KMT2ADPYDPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |