Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | DPYD | Q12882 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472862 | 0.85 | IMPDH2 (0.40) | MAOBPNPDPYDPOLBGAA | |
| SCHEMBL6472836 | 0.83 | NR4A1 (0.47) | PNPDPYDSMN1; SMN2 | |
| SCHEMBL6652475 | 0.83 | DPYD (0.41) | PNPDPYDPOLBSMN1; SMN2 | |
| SCHEMBL6472856 | 0.83 | MAOB (0.48) | MAOBARDAOPOLBIMPDH2 | |
| SCHEMBL6472151 | 0.81 | PARP10 (0.49) | MAOBPNPDPYD | |
| SCHEMBL6647198 | 0.81 | PNP (0.40) | PNPDPYDPOLBGAASMN1; SMN2 | |
| SCHEMBL6652195 | 0.79 | MAPK14 (0.38) | MAOBPNPDPYDDAOGAA | |
| SCHEMBL6472682 | 0.79 | LMNA (0.49) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6471640 | 0.79 | DPYD (0.41) | MAOBPNPDPYDPOLBGAA | |
| SCHEMBL6471088 | 0.76 | THRA (0.45) | DPYDPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |