Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2340159 | 0.81 | LDHA (0.56) | LDHAALDH1A1GAA | |
| SCHEMBL20543742 | 0.79 | LDHA (0.50) | LDHASLC6A4PPARGPPARAALDH1A1 | |
| SCHEMBL19559508 | 0.76 | SLC6A4 (0.55) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL2339593 | 0.72 | LDHA (0.56) | LDHASLC6A4PPARGPPARACYP1A2 | |
| SCHEMBL28188092 | 0.72 | SLC6A4 (0.54) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8430509 | 0.71 | LTA4H (0.56) | LDHASLC6A4PPARGPPARAALDH1A1 | |
| SCHEMBL27454162 | 0.70 | LDHA (0.77) | LDHASLC6A4PPARGPPARACYP1A2 | |
| SCHEMBL4474755 | 0.70 | L3MBTL1 (0.42) | LDHACYP1A2ALDH1A1GAAFFAR1 | |
| SCHEMBL490716 | 0.70 | LDHA (1.00) | LDHASLC6A4PPARGPPARACYP1A2 | |
| SCHEMBL10436394 | 0.68 | LDHA (0.76) | LDHASLC6A4PPARGPPARACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598232-B2 | Amino-substituted (E)-2,6-dialkoxystyryl 4-substituted-benzylsulfones for treating proliferative disorders | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2009-10-06 | — | — | US | disclosed |