SCHEMBL4483045

SCHEMBL4483045

CCN(c1ccc(NC2CCCCCCC2)cc1)C1CCCCCCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
MAPT P10636 2/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
RAB9A P51151 4/20 0.39
SYK P43405 2/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
EPHX1 P07099 1/20 0.38
KDM4E B2RXH2 1/20 0.38
APAF1 O14727 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPK1 P28482 1/20 0.38
BLM P54132 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NPC1 O15118 2/20 0.36
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
ADORA3 P0DMS8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9514252 0.87 RAB9A (0.43) LMNAPOLBRAB9AMEN1KMT2A
SCHEMBL4489491 0.85 TRPV1 (0.40) LMNAMAPTPOLBGAAMEN1
SCHEMBL4484272 0.85 ADH1C (0.41) GAARAB9AMEN1KMT2ACNR1
SCHEMBL4474636 0.85 ADH1C (0.41) GAARAB9AMEN1KMT2ACNR1
SCHEMBL4477077 0.84 MC4R (0.41) LMNAMAPTPOLBGAAMEN1
SCHEMBL4485641 0.84 S1PR1 (0.39) LMNAMAPTPOLBGAAMEN1
SCHEMBL9514566 0.81 ATM (0.43) LMNAMAPTGAARAB9AMEN1
SCHEMBL9513121 0.81 ATM (0.43) LMNAMAPTGAARAB9AMEN1
SCHEMBL4487922 0.79 EPHX1 (0.44) LMNAMAPTPOLBGAARAB9A
SCHEMBL4479148 0.78 MAPT (0.46) LMNAMAPTPOLBGAARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090156441-A1 Cycloalkyl phenylenediamines as deposit control agents for lubricants GREAT LAKES CHEMICAL GLOBAL, INC. 2009-06-18 US claimed
US-20090156441-A1 Cycloalkyl phenylenediamines as deposit control agents for lubricants GREAT LAKES CHEMICAL GLOBAL, INC. 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156441-A1 Cycloalkyl phenylenediamines as deposit control agents for lubricants C5, C9, C1S LMNA 3274/4885MAPT 2214/4885POLB 513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.