Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | CETP | P11597 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Acetate SCHEMBL11321872 | 0.98 | PPARG (0.52) | PPARGPPARAALDH1A1KCNH2RARB | |
| SCHEMBL27676149 | 0.88 | ALDH1A1 (0.54) | PPARGPPARAALDH1A1KCNH2RARB | |
| Acetic Acid Butyl Ester SCHEMBL11329285 | 0.88 | ALDH1A1 (0.55) | PPARGPPARAALDH1A1KCNH2RARB | |
| Ethyl Acetate SCHEMBL1465262 | 0.87 | THRB (0.53) | ALDH1A1RARBMAPTMEN1RARA | |
| Ethyl Acetate SCHEMBL718108 | 0.87 | THRB (0.53) | ALDH1A1RARBMAPTMEN1RARA | |
| Acetic Acid Methyl Ester SCHEMBL27476027 | 0.87 | ALDH1A1 (0.54) | PPARGPPARAALDH1A1KCNH2RARB | |
| Acetic Acid Methyl Ester SCHEMBL27476029 | 0.87 | ALDH1A1 (0.54) | PPARGPPARAALDH1A1KCNH2RARB | |
| Acetic Acid Methyl Ester SCHEMBL27492060 | 0.87 | ALDH1A1 (0.54) | PPARGPPARAALDH1A1KCNH2RARB | |
| Acetic Acid SCHEMBL27621705 | 0.86 | ALDH1A1 (0.61) | ALDH1A1KCNH2RARBMAPTRXFP1 | |
| Acetic Acid SCHEMBL27798118 | 0.86 | ALDH1A1 (0.61) | ALDH1A1KCNH2RARBMAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281120-A1 | BICYCLIC HETEROCYCLIC COMPOUND | ONO PHARMACEUTICAL CO., LTD (JP) | 2009-11-12 | — | — | US | disclosed |
| EP-1961745-A1 | BICYCLIC HETEROCYCLIC COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-08-27 | — | — | EP | disclosed |
| US-5070206-A | INHIBITORS OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE; ANTICHOLESTEROL, ANTILIPEMIC | BRISTOL-MYERS COMPANY (US) | 1991-12-03 | — | — | US | disclosed |
| US-5010205-A | Antihypercholesterolemic tetrazol-1-yl intermediates | BRISTOL-MYERS COMPANY (US) | 1991-04-23 | — | — | US | disclosed |
| EP-0355820-A1 | Antihypercholesterolemic tetrazol-1-yl compounds | Bristol-Myers Squibb Company (US) | 1990-02-28 | — | — | EP | disclosed |
| US-4870187-A | ANTILIPEMIC, ATHEROSCLEROSIS | BRISTOL-MYERS COMPANY (US) | 1989-09-26 | — | — | US | disclosed |
| US-4212974-A | POLYMER STABILIZERS | SANKYO COMPANY LIMITED (JP) | 1980-07-15 | — | — | US | disclosed |
| US-4141883-A | Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives | SANKYO COMPANY, LIMITED (JP) | 1979-02-27 | — | — | US | disclosed |
| US-4125533-A | STABILIZERS | SANKYO CO. LTD. (JP) | 1978-11-14 | — | — | US | disclosed |
| US-4016168-A | STABILIZERS FOR POLYMERS | SANKYO COMPANY LIMITED (JA) | 1977-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281120-A1 | BICYCLIC HETEROCYCLIC COMPOUND | CRHR1, NR3C1, CNR1 | PPARG 579/4885PPARA 1000/4885ALDH1A1 3438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.