Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.53 |
| ▸ | THRA | P10827 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | TACR2 | P21452 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SHBG | P04278 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Acetate SCHEMBL1465262 | 1.00 | THRB (0.53) | THRBTHRAALDH1A1ESR1ADRA2A | |
| Ethyl Acetate SCHEMBL4477186 | 0.87 | PPARG (0.53) | THRBTHRAALDH1A1RARBMEN1 | |
| Ethyl Acetate SCHEMBL11321872 | 0.86 | PPARG (0.52) | THRBTHRAALDH1A1RARBMEN1 | |
| Acetic Acid Butyl Ester SCHEMBL6704840 | 0.84 | ALDH1A1 (0.50) | THRBTHRAALDH1A1ESR1ADRA2A | |
| SCHEMBL4252573 | 0.83 | THRA (0.55) | THRBTHRAALDH1A1ESR1ADRA2A | |
| SCHEMBL13783933 | 0.83 | ALDH1A1 (0.59) | THRBTHRAALDH1A1ESR1ADRA2A | |
| SCHEMBL19291196 | 0.83 | THRA (0.55) | THRBTHRAALDH1A1ESR1ADRA2A | |
| SCHEMBL3675245 | 0.83 | CTDSP1 (0.49) | THRBTHRAALDH1A1KDM4ELMNA | |
| SCHEMBL80498 | 0.82 | ESR1 (0.65) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL168031 | 0.82 | ESR1 (0.65) | ALDH1A1ESR1ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368424-B | Polymerizable compounds and their use in liquid crystal displays | 默克专利股份有限公司 | 2022-06-03 | — | — | CN | disclosed |
| EP-3387089-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2019-10-02 | — | — | EP | disclosed |
| US-20180371321-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2018-12-27 | — | — | US | disclosed |
| EP-3387089-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | Merck Patent GmbH (DE) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017097401-A9 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2018-09-07 | — | — | WO | disclosed |
| CN-108368424-A | Polymerizable compounds and their use in liquid crystal displays | 默克专利股份有限公司 | 2018-08-03 | — | — | CN | disclosed |
| WO-2017097401-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2017-06-15 | — | — | WO | disclosed |
| US-8986856-B2 | Iridium complex and organic light-emitting element including the same | CANON KABUSHIKI KAISHA (JP) | 2015-03-24 | — | — | US | disclosed |
| US-8980444-B2 | Iridium complex and organic light-emitting device including the same | CANON KABUSHIKI KAISHA (JP) | 2015-03-17 | — | — | US | disclosed |
| CN-104245670-A | Benzofluorene compound, material for light-emitting layer which is produced using said compound, and organic electroluminescent element | JNC CORP | 2014-12-24 | — | — | CN | disclosed |
| US-20120235134-A1 | NOVEL IRIDIUM COMPLEX AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-09-20 | — | — | US | disclosed |
| US-8124780-B2 | Benzimidazole compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-02-28 | — | — | US | disclosed |
| CN-101160306-B | Benzimidazole compounds | EISAI R&D MAN CO LTD | 2011-11-02 | — | — | CN | disclosed |
| EP-1870409-B1 | BENZIMIDAZOLE COMPOUNDS | EISAI R&D MAN CO LTD (JP) | 2010-05-12 | — | — | EP | disclosed |
| US-20090203911-A1 | BENZIMIDAZOLE COMPOUND | MIYAZAWA SHUHEI | 2009-08-13 | — | — | US | disclosed |
| US-7425634-B2 | Benzimidazole compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-09-16 | — | — | US | disclosed |
| CN-101160306-A | Benzimidazole compounds | EISAI R&D MAN CO LTD (JP) | 2008-04-09 | — | — | CN | disclosed |
| EP-1870409-A1 | BENZIMIDAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-12-26 | — | — | EP | disclosed |
| US-20070015782-A1 | Benzimidazole compound | EISAI CO., LTD. | 2007-01-18 | — | — | US | disclosed |
| US-20070010542-A1 | Benzimidazole compound | EISAI CO., LTD. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120235134-A1 | NOVEL IRIDIUM COMPLEX AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | OCIAD1, ORC3, PPOX | THRB 2955/4885THRA 3002/4885ALDH1A1 902/4885 |
| US-20070010542-A1 | Benzimidazole compound | HRH2, GIPR, HRH4 | THRB 3064/4885THRA 2223/4885ALDH1A1 1028/4885 |
| US-20090203911-A1 | BENZIMIDAZOLE COMPOUND | HRH2, HRH4, HRH1 | THRB 2987/4885THRA 2117/4885ALDH1A1 1053/4885 |
| US-20070015782-A1 | Benzimidazole compound | HRH2, GIPR, HRH4 | THRB 3064/4885THRA 2223/4885ALDH1A1 1028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.