Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ACLY | P53396 | 3/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | SLC9A3 | P48764 | 4/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL448018 | 0.89 | LMNA (0.40) | ALDH1A1ACLYCXCR2PDK1PDK2 | |
| SCHEMBL30795090 | 0.89 | LMNA (0.40) | ALDH1A1ACLYCXCR2PDK1PDK2 | |
| SCHEMBL30794423 | 0.88 | GSTO1 (0.44) | ALDH1A1ACLYGSTO1PDK1PDK2 | |
| SCHEMBL439442 | 0.88 | GSTO1 (0.44) | ALDH1A1ACLYGSTO1PDK1PDK2 | |
| SCHEMBL451705 | 0.87 | ALDH1A1 (0.42) | ALDH1A1ACLYCXCR2GSTO1PDK1 | |
| SCHEMBL30794605 | 0.87 | ALDH1A1 (0.42) | ALDH1A1ACLYCXCR2GSTO1PDK1 | |
| SCHEMBL30794731 | 0.83 | CAMK2A (0.41) | ALDH1A1CAMK2A | |
| SCHEMBL448080 | 0.83 | CAMK2A (0.41) | ALDH1A1CAMK2A | |
| SCHEMBL449648 | 0.83 | PTGS2 (0.49) | MAPTFTO | |
| SCHEMBL30795150 | 0.83 | PTGS2 (0.49) | MAPTFTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 353 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3441088-B1 | ANTIBODY-DRUG CONJUGATE COMPRISING MODIFIED ANTIBODY | ALTEOGEN INC (KR) | 2022-10-05 | — | — | EP | claimed |
| EP-3521314-B1 | ANTIBODY-DRUG CONJUGATES AND USE THEREOF IN THERAPY | MC SAF (FR) | 2021-02-24 | — | — | EP | claimed |
| EP-2818480-B1 | MODIFIED ANTIBODY IN WHICH MOTIF COMPRISING CYSTEINE RESIDUE IS BOUND, MODIFIED ANTIBODY-DRUG CONJUGATE COMPRISING THE MODIFIED ANTIBODY, AND PRODUCTION METHOD FOR SAME | ALTEOGEN INC (KR) | 2020-08-26 | — | — | EP | claimed |
| EP-3077007-B1 | REVERSIBLE PEGYLATION OF NANOCARRIERS | UNIV FREIBURG ALBERT LUDWIGS (DE) | 2019-11-20 | — | — | EP | claimed |
| CN-109364261-A | A kind of controllable percutaneous drug administration preparation and preparation method thereof based on frame nucleic acid | 中国科学院上海应用物理研究所 | 2019-02-22 | — | — | CN | claimed |
| CN-109069657-A | Antibody-drug conjugates comprising modified antibodies | 阿特根公司 | 2018-12-21 | — | — | CN | claimed |
| EP-2167103-B1 | SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTICANCER AGENTS | ALLEXCEL INC (US) | 2017-03-01 | — | — | EP | claimed |
| CN-105592859-A | Novel antibody-drug conjugates and the use of same in therapy | UNIV FRANCOIS RABELAIS DE TOURS | 2016-05-18 | — | — | CN | claimed |
| CN-105561324-A | Self-assembly amphiphilic polymer used as anticancer agent | ALLEXCEL INC | 2016-05-11 | — | — | CN | claimed |
| CN-101795695-B | Self-assembling amphiphilic polymers as anticancer agents | ALLEXCEL, INC. (US) | 2016-01-06 | — | — | CN | claimed |
| CN-1511044-A | Elogated and multiple spacers in activatible prodrugs | — | 2004-07-07 | — | — | CN | claimed |
| CN-1117760-C | Lysosomal enzyme-cleavable antitumor drug conjugates | BRISTOL MYERS SQUIBB CO (US) | 2003-08-13 | — | — | CN | claimed |
| EP-1039904-B1 | SYNERGISTIC ANTIMICROBIAL COMPOSITIONS | GOODMAN THOMAS C (US) | 2003-05-28 | — | — | EP | claimed |
| CN-1399561-A | Conjugates with cleavable linkages for use in liposomes | ALZA CORP (US) | 2003-02-26 | — | — | CN | claimed |
| EP-0624377-B1 | Lysosomal enzyme-cleavable antitumor drug conjugates | BRISTOL MYERS SQUIBB CO (US) | 2002-01-23 | — | — | EP | claimed |
| WO-2001090300-A2 | SNAP BACK STEALTH OLIGONUCLEOTIDE | FORD JOHN P (US) | 2001-11-29 | — | — | WO | claimed |
| CN-1100426-A | Lysosomal enzyme-cleavable antitumor drug conjugates | BRISTOL MYERS SQUIBB CO (US) | 1995-03-22 | — | — | CN | claimed |
| EP-0324109-B1 | 6-SUBSTITUTED MITOMYCIN ANALOGS | UNIVERSITY PATENTS, INC. (US) | 1993-09-29 | — | — | EP | claimed |
| CN-1040593-A | Has E09 of reduced bone marrow toxicity and its production and application | UNIV GEORGETOWN (US) | 1990-03-21 | — | — | CN | claimed |
| EP-0074245-B1 | PROCESS FOR PRODUCING MITOMYCIN A BY FERMENTATION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-02-12 | — | — | EP | claimed |