Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4505680 | 0.99 | IGF1R (0.34) | IGF1RALDH1A1POLBKMT2A | |
| SCHEMBL4756903 | 0.71 | IGF1R (0.40) | IGF1RALDH1A1POLBKMT2A | |
| SCHEMBL4499054 | 0.65 | IGF1R (0.35) | IGF1RALDH1A1POLBKMT2A | |
| SCHEMBL13919312 | 0.64 | IGF1R (0.48) | IGF1RALDH1A1POLBKMT2A | |
| SCHEMBL4208158 | 0.64 | IGF1R (0.76) | IGF1RALDH1A1POLBKMT2A | |
| SCHEMBL4498917 | 0.61 | IGF1R (0.54) | IGF1RALDH1A1POLBKMT2A | |
| SCHEMBL7122223 | 0.60 | IGF1R (0.71) | IGF1RALDH1A1POLBKMT2A | |
| SCHEMBL5403308 | 0.60 | LMNA (0.45) | IGF1RALDH1A1POLBKMT2A | |
| SCHEMBL5415486 | 0.60 | ALDH1A1 (0.45) | IGF1RALDH1A1POLBKMT2A | |
| SCHEMBL9735543 | 0.59 | IGF1R (0.37) | IGF1RALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504429-B2 | Tyrosine kinase inhibitors | MERCK & CO., INC. (US) | 2009-03-17 | — | — | US | claimed |