SCHEMBL4480973

SCHEMBL4480973

Cc1cccc(C(=O)NC(C)C)c1NC(=O)c1cc(C(F)(F)F)nn1-c1ccccc1CNC(=O)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 6/20 0.46
F2 P00734 3/20 0.42
CARM1 Q86X55 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5653070 0.96 F10 (0.48) F10F2CARM1
SCHEMBL4481841 0.89 F10 (0.46) F10F2CARM1
SCHEMBL4484650 0.89 F10 (0.53) F10F2CARM1
SCHEMBL4477762 0.86 CARM1 (0.42) F10F2CARM1
SCHEMBL1383820 0.85 CRACR2A (0.45) F10F2CARM1
SCHEMBL4769625 0.84 CARM1 (0.42) F10F2CARM1
SCHEMBL3278308 0.82 KLKB1 (0.50) CARM1
SCHEMBL4666449 0.78 AURKA (0.48) CARM1
SCHEMBL3276731 0.78 RIPK1 (0.40) CARM1
SCHEMBL29393434 0.76 DHODH (0.39) CARM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7541377-B2 Substituted anthranilamides for controlling invertebrate pests E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-02 US claimed