SCHEMBL5653070

SCHEMBL5653070

Cc1cccc(C(=O)NC(C)C)c1NC(=O)c1cc(C(F)(F)F)nn1-c1ccccc1CN.Cc1cccc(C(=O)NC(C)C)c1NC(=O)c1cc(C(F)(F)F)nn1-c1ccccc1CNC(=O)C(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F10 P00742 10/20 0.48
F2 P00734 6/20 0.48
KLKB1 P03952 3/20 0.44
PROC P04070 1/20 0.44
PRSS1 P07477 1/20 0.44
CARM1 Q86X55 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4480973 0.96 F10 (0.46) F10F2CARM1
SCHEMBL4484650 0.93 F10 (0.53) F10F2KLKB1PROCPRSS1
SCHEMBL4481841 0.86 F10 (0.46) F10F2KLKB1PROCPRSS1
SCHEMBL4477762 0.83 CARM1 (0.42) F10F2KLKB1CARM1
SCHEMBL1383820 0.82 CRACR2A (0.45) F10F2KLKB1CARM1
SCHEMBL4769625 0.81 CARM1 (0.42) F10F2KLKB1CARM1
SCHEMBL3278308 0.79 KLKB1 (0.50) KLKB1CARM1
SCHEMBL4666449 0.76 AURKA (0.48) KLKB1CARM1
SCHEMBL3276731 0.75 RIPK1 (0.40) KLKB1CARM1
SCHEMBL29393434 0.73 DHODH (0.39) KLKB1CARM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070203201-A1 Substituted anthranilamides for controlling invertebrate pests FINKELSTEIN BRUCE L 2007-08-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203201-A1 Substituted anthranilamides for controlling invertebrate pests ANTXR2, PRXL2A, F9 F10 393/4885F2 383/4885KLKB1 4573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.