Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.53 |
| ▸ | F2 | P00734 | 8/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.49 |
| ▸ | PROC | P04070 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5653070 | 0.93 | F10 (0.48) | F10F2KLKB1PROCPRSS1 | |
| SCHEMBL4481841 | 0.92 | F10 (0.46) | F10F2KLKB1PROCPRSS1 | |
| SCHEMBL4480973 | 0.89 | F10 (0.46) | F10F2CARM1 | |
| SCHEMBL1383820 | 0.88 | CRACR2A (0.45) | F10F2KLKB1CARM1 | |
| SCHEMBL4477762 | 0.87 | CARM1 (0.42) | F10F2KLKB1CARM1 | |
| SCHEMBL4769625 | 0.87 | CARM1 (0.42) | F10F2KLKB1CARM1 | |
| SCHEMBL3278308 | 0.85 | KLKB1 (0.50) | KLKB1CARM1 | |
| SCHEMBL4666449 | 0.81 | AURKA (0.48) | KLKB1CARM1 | |
| SCHEMBL3276731 | 0.80 | RIPK1 (0.40) | KLKB1CARM1 | |
| SCHEMBL29393434 | 0.78 | DHODH (0.39) | KLKB1CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541377-B2 | Substituted anthranilamides for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-06-02 | — | — | US | claimed |