SCHEMBL448114

SCHEMBL448114

CC(C)(C)OC(=O)NCCc1ccc(N)cc1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 0.58
CA1 P00915 6/20 0.58
ESRRG P62508 1/20 0.57
NAMPT P43490 1/20 0.54
IDO1 P14902 1/20 0.48
TDP1 Q9NUW8 2/20 0.46
MAPT P10636 1/20 0.46
NQO2 P16083 1/20 0.46
CA12 O43570 2/20 0.46
CA9 Q16790 2/20 0.46
LMNA P02545 1/20 0.46
GLA P06280 1/20 0.46
KMT2A Q03164 1/20 0.46
PTGER4 P35408 1/20 0.45
CTSK P43235 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL2728968 0.96 CA2 (0.55) CA2CA1ESRRGNAMPTIDO1
SCHEMBL580221 0.93 CA2 (0.53) CA2CA1ESRRGNAMPTIDO1
SCHEMBL24413718 0.92 CA2 (0.52) CA2CA1ESRRGNAMPTIDO1
SCHEMBL4039313 0.91 CA1 (0.56) CA2CA1ESRRGNAMPTIDO1
SCHEMBL5264226 0.91 CA2 (0.58) CA2CA1ESRRGNAMPTIDO1
SCHEMBL938186 0.90 CA1 (0.55) CA2CA1ESRRGNAMPTTDP1
SCHEMBL16264885 0.88 TDP1 (0.55) CA2CA1ESRRGTDP1CA12
SCHEMBL23449213 0.88 CA2 (0.58) CA2CA1NAMPTIDO1TDP1
SCHEMBL20208983 0.87 CA2 (0.55) CA2CA1ESRRGNAMPTIDO1
SCHEMBL30958195 0.86 IDO1 (0.48) CA2CA1ESRRGNAMPTIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114262321-A Bistable light-regulated small-molecule protein degradation agent, preparation method and application 中国药科大学 2022-04-01 CN claimed
WO-2015162536-A1 NOVEL PROCESS FOR PREPARATION OF MIRABEGRON AND IT'S INTERMEDIATE CALYX CHEMICALS AND PHARMACEUTICALS LTD. (IN) 2015-10-29 WO claimed
EP-4710923-A2 INDOLE AHR INHIBITORS AND USES THEREOF Ikena Oncology, Inc. (US) 2026-03-18 EP disclosed
EP-3814356-B1 TRIAZOLOTRIAZINE DERIVATIVES AS A2A RECEPTOR ANTAGONISTS ZHEJIANG VIMGREEN PHARMACEUTICALS LTD (CN) 2026-03-11 EP disclosed
US-12540143-B2 Methods and compositions for targeted protein degradation RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) 2026-02-03 US disclosed
US-12516018-B2 Solid-solid phase change aromatic azo compounds, method of manufacture, and use for thermal energy storage and release BRANDEIS UNIVERSITY (US) 2026-01-06 US disclosed
EP-3612030-B1 INDOLE AHR INHIBITORS AND USES THEREOF IKENA ONCOLOGY INC (US) 2025-12-24 EP disclosed
US-20250262308-A1 Compositions and Methods for Modulating Dopamine Receptor Activity THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-08-21 US disclosed
US-20250122205-A1 INDOLE AHR INHIBITORS AND USES THEREOF PAHR THERAPEUTICS, INC. 2025-04-17 US disclosed
US-20250115600-A1 COVALENT MODIFIERS OF AKT1 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. 2025-04-10 US disclosed
EP-4522172-A1 COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY The Regents of the University of California (US) 2025-03-19 EP disclosed
WO-1997012870-A1 TETRAHYDROQUINOLINES AS NMDA ANTAGONISTS GLAXO WELLCOME S.P.A. (IT) 1997-04-10 WO disclosed
US-5563141-A INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION ZENECA LIMITED (GB) 1996-10-08 US disclosed
EP-0690847-A1 HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS ZENECA LIMITED (GB) 1996-01-10 EP disclosed
US-5451677-A Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity MERCK & CO., INC. (US) 1995-09-19 US disclosed
WO-1995017888-A1 PHENYLMETHYL HEXANAMIDES, AND THE USE THEREOF SMITHKLINE BEECHAM CORPORATION (US) 1995-07-06 WO disclosed
WO-1994022835-A2 HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS ZENECA LIMITED (GB) 1994-10-13 WO disclosed
EP-0611003-A1 Substituted phenyl sulfonamides as selective B3 agonists for the treatment of diabetes and obesity MERCK & CO. INC. (US) 1994-08-17 EP disclosed
EP-0369344-B1 N-arylation of isatins ABBOTT LAB (US) 1994-04-06 EP disclosed
US-5151518-A N-arylation of isatins ABBOTT LABORATORIES (US) 1992-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115600-A1 COVALENT MODIFIERS OF AKT1 AND USES THEREOF AKT1, AKT1S1, AKT2 CA2 4004/4885CA1 3828/4885ESRRG 1745/4885
US-20250122205-A1 INDOLE AHR INHIBITORS AND USES THEREOF AHR, ARNT, IDO1 CA2 2880/4885CA1 3888/4885ESRRG 338/4885
US-12540143-B2 Methods and compositions for targeted protein degradation ADRM1, NCOR1, KDELR1 CA2 4115/4885CA1 3519/4885ESRRG 117/4885
US-20250262308-A1 Compositions and Methods for Modulating Dopamine Receptor Activity PARK7, PRLHR, SNCA CA2 3865/4885CA1 2987/4885ESRRG 322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.