SCHEMBL580221

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL448114	0.93	CA2 (0.58)	CA2CA1ESRRGNAMPTCA12
	Acetic Acid SCHEMBL2728968	0.89	CA2 (0.55)	CA2CA1ESRRGNAMPTCA12
	SCHEMBL4449400	0.88	KDM4E (0.53)	CA2CA1ESRRGNAMPTCA12
	SCHEMBL13886599	0.88	EPHX2 (0.59)	CA2CA1NAMPTEPHX2PLAAT3
	SCHEMBL9101687	0.86	LTA4H (0.57)	CA2CA1NAMPTGLAKMT2A
	SCHEMBL9108821	0.86	EPHX2 (0.57)	CA2CA1NAMPTCA12CA9
	SCHEMBL24413718	0.85	CA2 (0.52)	CA2CA1ESRRGNAMPTCA12
	SCHEMBL4039313	0.85	CA1 (0.56)	CA2CA1ESRRGNAMPTCA12
	SCHEMBL5264226	0.84	CA2 (0.58)	CA2CA1ESRRGNAMPTCA12
	SCHEMBL2872438	0.84	EPHX2 (0.61)	CA2CA1NAMPTGLAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.