Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4483736 | 0.84 | POLB (0.41) | EPHX1LMNAMAPTPOLBGAA | |
| SCHEMBL4485641 | 0.78 | S1PR1 (0.39) | EPHX1LMNAMAPTPOLBGAA | |
| SCHEMBL8702788 | 0.74 | EPHX1 (0.59) | EPHX1LMNAMAPTPOLBGAA | |
| SCHEMBL11475322 | 0.73 | RAB9A (0.35) | EPHX1LMNAPOLBALDH1A1MEN1 | |
| SCHEMBL4487922 | 0.73 | EPHX1 (0.44) | EPHX1LMNAMAPTPOLBGAA | |
| SCHEMBL4479148 | 0.73 | MAPT (0.46) | EPHX1LMNAMAPTPOLBGAA | |
| SCHEMBL4491483 | 0.73 | HRH4 (0.36) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4483045 | 0.73 | LMNA (0.41) | EPHX1LMNAMAPTPOLBGAA | |
| SCHEMBL4489912 | 0.71 | ALDH1A1 (0.50) | EPHX1LMNAPOLBALDH1A1MEN1 | |
| SCHEMBL4476002 | 0.71 | MAPT (0.47) | EPHX1LMNAMAPTPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156441-A1 | Cycloalkyl phenylenediamines as deposit control agents for lubricants | GREAT LAKES CHEMICAL GLOBAL, INC. | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156441-A1 | Cycloalkyl phenylenediamines as deposit control agents for lubricants | C5, C9, C1S | EPHX1 1205/4885LMNA 3274/4885MAPT 2214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.