SCHEMBL4485641

SCHEMBL4485641

CC(C)CN(c1ccc(NC2CCCCC2)cc1)C1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.39
S1PR3 Q99500 1/20 0.39
RORC P51449 7/20 0.38
IDO1 P14902 2/20 0.38
MAPT P10636 2/20 0.38
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
EPHX1 P07099 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
APAF1 O14727 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPK1 P28482 1/20 0.36
BLM P54132 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4471183 0.86 CCKBR (0.39) S1PR1S1PR3IDO1MEN1KMT2A
SCHEMBL4497068 0.84 IDO1 (0.37) RORCIDO1MAPTPOLBKDM4E
SCHEMBL4483045 0.84 LMNA (0.41) MAPTLMNAPOLBGAAEPHX1
SCHEMBL4489491 0.79 TRPV1 (0.40) MAPTLMNAPOLBGAAEPHX1
SCHEMBL4477077 0.78 MC4R (0.41) MAPTLMNAPOLBGAAEPHX1
SCHEMBL4482691 0.78 EPHX1 (0.37) RORCMAPTLMNAPOLBGAA
SCHEMBL4483736 0.78 POLB (0.41) MAPTLMNAPOLBGAAEPHX1
SCHEMBL4487922 0.75 EPHX1 (0.44) MAPTLMNAPOLBGAAEPHX1
SCHEMBL4479148 0.75 MAPT (0.46) IDO1MAPTLMNAPOLBGAA
SCHEMBL4475084 0.74 CCKBR (0.38) S1PR1S1PR3IDO1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090156441-A1 Cycloalkyl phenylenediamines as deposit control agents for lubricants GREAT LAKES CHEMICAL GLOBAL, INC. 2009-06-18 US claimed
US-20090156441-A1 Cycloalkyl phenylenediamines as deposit control agents for lubricants GREAT LAKES CHEMICAL GLOBAL, INC. 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156441-A1 Cycloalkyl phenylenediamines as deposit control agents for lubricants C5, C9, C1S S1PR1 2596/4885S1PR3 1968/4885RORC 4314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.