Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4830005 | 0.98 | — | — | |
| Potassium SCHEMBL29519191 | 0.98 | — | — | |
| SCHEMBL18775436 | 0.81 | LMNA (0.33) | — | |
| SCHEMBL15910483 | 0.75 | — | — | |
| SCHEMBL4485232 | 0.73 | — | — | |
| SCHEMBL10445030 | 0.73 | — | — | |
| SCHEMBL10806666 | 0.69 | THRB (0.38) | THRB | |
| SCHEMBL21790201 | 0.69 | THRB (0.38) | THRB | |
| SCHEMBL8041239 | 0.68 | LMNA (0.50) | — | |
| SCHEMBL8040302 | 0.67 | LMNA (0.41) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10954194-B2 | 18-20 member bi-polycyclic compounds | Haro Pharmaceuticals Inc. (US) | 2021-03-23 | — | — | US | disclosed |
| US-10752591-B2 | 18-20 member bi-polycyclic compounds | Haro Pharmaceuticals Inc. (US) | 2020-08-25 | — | — | US | disclosed |
| US-10377715-B2 | 18-20 member bi-polycyclic compounds | Haro Pharmaceuticals Inc. (US) | 2019-08-13 | — | — | US | disclosed |
| US-20170114019-A1 | 18-20 MEMBER BI-POLYCYCLIC COMPOUNDS | HARO PHARMACEUTICAL INC. | 2017-04-27 | — | — | US | disclosed |
| WO-2015188015-A1 | 18-20 MEMBER BI-POLYCYCLIC COMPOUNDS | HARO PHARMACEUTICAL INC. (US) | 2015-12-10 | — | — | WO | disclosed |
| US-20090306380-A1 | Process for preparing 4-amino-2-alkylthio-5-pyrimidinecarbaldehyde | UBE INDUSTRIES, LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
| CN-100432073-C | 6-alkoxy-pyrido-pyrimidines as p-38 MAP kinase inhibitors | HOFFMANN LA ROCHE (CH) | 2008-11-12 | — | — | CN | disclosed |
| CN-100376571-C | 6-substituted pyrido-pyrimidines | HOFFMANN LA ROCHE (CH) | 2008-03-26 | — | — | CN | disclosed |
| CN-1675207-A | 6-alkoxy-pyrido-pyrimidines as p-38 MAP kinase inhibitors | HOFFMANN LA ROCHE (CH) | 2005-09-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306380-A1 | Process for preparing 4-amino-2-alkylthio-5-pyrimidinecarbaldehyde | NUDT1, DPYD, TPMT | THRB 2769/4885 |
| US-10752591-B2 | 18-20 member bi-polycyclic compounds | TNNI3, TNNC1, MYLK2 | THRB 1612/4885 |
| US-10377715-B2 | 18-20 member bi-polycyclic compounds | CKMT1A; CKMT1B, MYLK2, CPT1B | THRB 3024/4885 |
| US-10954194-B2 | 18-20 member bi-polycyclic compounds | BRCA1, UGT2B17, TP53 | THRB 3131/4885 |
| US-20170114019-A1 | 18-20 MEMBER BI-POLYCYCLIC COMPOUNDS | CKMT1A; CKMT1B, MYLK2, CPT1B | THRB 3024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.