Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614828 | 0.79 | — | — | |
| SCHEMBL6755235 | 0.78 | HPGD (0.55) | ALDH1A1SMN1; SMN2HPGDKDM4ELMNA | |
| SCHEMBL340868 | 0.75 | GPR55 (0.46) | — | |
| SCHEMBL30505689 | 0.71 | CYP2C9 (0.50) | SMN1; SMN2HPGDKDM4ELMNAMEN1 | |
| SCHEMBL21490412 | 0.71 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2HPGDKDM4ELMNA | |
| SCHEMBL3041845 | 0.71 | HPGD (0.53) | ALDH1A1SMN1; SMN2HPGDKDM4ELMNA | |
| SCHEMBL8763678 | 0.71 | SLC2A1 (0.44) | ALDH1A1TSHR | |
| SCHEMBL11716781 | 0.71 | CYP2A6 (0.42) | ALDH1A1L3MBTL1TSHR | |
| SCHEMBL11859580 | 0.71 | HSD17B10 (0.42) | ALDH1A1TSHRCYP2C9 | |
| SCHEMBL6755241 | 0.70 | HSD17B10 (0.66) | ALDH1A1SMN1; SMN2HPGDKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550605-B2 | Process for preparation of an anitdepressant compound | SUN PHARMACEUTICAL INDUSTRIES LTD. (IN) | 2009-06-23 | — | — | US | disclosed |
| US-20070191616-A1 | Process for preparation of an antidepressant compound | SUN PHAMACEUUTICAL INDUSTRIES LTD. (IN) | 2007-08-16 | — | — | US | disclosed |
| WO-2006027798-A2 | A PROCESS FOR PREPARATION OF AN ANTIDEPRESSANT COMPOUND | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2006-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191616-A1 | Process for preparation of an antidepressant compound | TPH1, TPH2, HTR4 | ALDH1A1 359/4885SMN1; SMN2 1243/4885HPGD 1866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.