Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877206 | 0.89 | ALOX5 (0.63) | ALOX5KMT2AMEN1FFAR1 | |
| SCHEMBL10695244 | 0.87 | ALOX5 (1.00) | ALOX5KMT2A | |
| SCHEMBL3366949 | 0.86 | KMT2A (0.70) | ALOX5KMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL9662985 | 0.85 | ALOX5 (0.97) | ALOX5KMT2A | |
| Water SCHEMBL3678915 | 0.84 | KMT2A (0.68) | ALOX5KMT2AALDH1A1MEN1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL3136984 | 0.84 | KMT2A (0.68) | ALOX5KMT2AALDH1A1MEN1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9130864 | 0.82 | KMT2A (0.66) | ALOX5KMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL14219225 | 0.81 | KMT2A (0.74) | ALOX5KMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL4064581 | 0.81 | KMT2A (1.00) | ALOX5KMT2AALDH1A1MEN1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6165650 | 0.81 | KMT2A (0.64) | ALOX5KMT2AALDH1A1MEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601245-A1 | CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF | Biofilm IP, LLC (US) | 2013-06-12 | — | — | EP | claimed |
| CN-103154095-A | Cyclosiloxane-substituted polysiloxane compounds, compositions containing the same, and methods of use thereof | BIOFILM IP LLC | 2013-06-12 | — | — | CN | claimed |
| CN-101326272-B | Hydraulic fluid composition and method of making same | COUNCIL SCIENT IND RES | 2012-10-10 | — | — | CN | claimed |
| WO-2012018403-A1 | CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF | BIOFILM IP, LLC (US) | 2012-02-09 | — | — | WO | claimed |
| CN-101326272-A | Hydraulic fluid composition and method of making same | COUNCIL SCIENT IND RES (IN) | 2008-12-17 | — | — | CN | claimed |
| US-9175141-B2 | Cyclosiloxane-substituted polysiloxane compounds, compositions containing the compounds and methods of use thereof | BIOFILM IP, LLC (US) | 2015-11-03 | — | — | US | disclosed |
| EP-2601245-A1 | CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF | Biofilm IP, LLC (US) | 2013-06-12 | — | — | EP | disclosed |
| CN-103154095-A | Cyclosiloxane-substituted polysiloxane compounds, compositions containing the same, and methods of use thereof | BIOFILM IP LLC | 2013-06-12 | — | — | CN | disclosed |
| CN-101326272-B | Hydraulic fluid composition and method of making same | COUNCIL SCIENT IND RES | 2012-10-10 | — | — | CN | disclosed |
| US-20120064022-A1 | CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF | BIOFILM, INC. | 2012-03-15 | — | — | US | disclosed |
| WO-2012018403-A1 | CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF | BIOFILM IP, LLC (US) | 2012-02-09 | — | — | WO | disclosed |
| CN-101326272-A | Hydraulic fluid composition and method of making same | COUNCIL SCIENT IND RES (IN) | 2008-12-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120064022-A1 | CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF | PIEZO1, DSC1, PFAS | ALOX5 403/4885KMT2A 2286/4885ALDH1A1 4496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.