SCHEMBL4496183

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4500058	0.91	SMN1; SMN2 (0.53)	LMNASMN1; SMN2HPGDSAPPEGFR
	SCHEMBL4489260	0.89	HPGDS (0.55)	LMNAHPGDSMN1; SMN2HPGDSAPP
	SCHEMBL4501469	0.88	APEX1 (0.49)	LMNAHPGDSMN1; SMN2HPGDSAPP
	SCHEMBL4484547	0.88	APP (0.48)	HPGDSMN1; SMN2HPGDSAPPEGFR
	SCHEMBL4487073	0.86	KDM4E (0.53)	HPGDHPGDSAPPEGFRRAB9A
	SCHEMBL4493680	0.85	MITF (0.56)	APPAURKARPS6KB1MEN1KMT2A
	SCHEMBL4489700	0.84	HIF1A (0.58)	LMNASMN1; SMN2RAB9AAURKARPS6KB1
	SCHEMBL4482214	0.84	AURKA (0.49)	SMN1; SMN2APPAURKARPS6KB1HIF1A
	SCHEMBL4477510	0.83	KDM4E (0.47)	HPGDSMN1; SMN2HPGDSGPBAR1EGFR
	SCHEMBL4487160	0.83	HPGDS (0.47)	HPGDSMN1; SMN2HPGDSEGFRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.