Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4483929 | 0.88 | NTRK1 (0.38) | NTRK1HTR2AHTR2CKDM4EMAPK1 | |
| SCHEMBL29371597 | 0.83 | GPR3 (0.45) | NTRK1HTR2AHTR2CKDM4EMAPK1 | |
| SCHEMBL7124714 | 0.83 | GPR3 (0.45) | NTRK1HTR2AHTR2CKDM4EMAPK1 | |
| SCHEMBL2978540 | 0.82 | MEN1 (0.41) | NTRK1HTR2AHTR2CKDM4EMAPK1 | |
| SCHEMBL21903029 | 0.78 | KDR (0.35) | NTRK1KDM4EMAPK1HSD17B10MAPT | |
| SCHEMBL27432871 | 0.75 | GPR3 (0.46) | NTRK1KDM4EMAPK1HSD17B10GPR3 | |
| SCHEMBL27432874 | 0.75 | GPR3 (0.46) | NTRK1KDM4EHSD17B10GPR3MAPT | |
| SCHEMBL18457082 | 0.75 | KDR (0.35) | NTRK1KDM4EMAPK1HSD17B10MAPT | |
| SCHEMBL13600300 | 0.74 | HTR2A (0.43) | NTRK1HTR2AHTR2CKDM4EMAPK1 | |
| SCHEMBL19159482 | 0.72 | HTR2A (0.47) | NTRK1HTR2AHTR2CKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635781-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2009-12-22 | — | — | US | disclosed |
| US-7635781-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2009-12-22 | — | — | US | disclosed |
| US-7635781-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2009-12-22 | — | — | US | disclosed |
| US-20080287692-A1 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2008-11-20 | — | — | US | disclosed |
| US-20080287692-A1 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2008-11-20 | — | — | US | disclosed |
| US-20080287692-A1 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2008-11-20 | — | — | US | disclosed |
| EP-1387827-B1 | SYNTHESIS OF CYCLOPENTADIENE DERIVATIVES | BASELL POLYOLEFINE GMBH (DE) | 2008-09-24 | — | — | EP | disclosed |
| US-7253292-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2007-08-07 | — | — | US | disclosed |
| US-7253292-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2007-08-07 | — | — | US | disclosed |
| US-20040236115-A1 | Synthesis of cyclopentadiene derivatives | EQUISTAR CHEMICALS, LP | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236115-A1 | Synthesis of cyclopentadiene derivatives | CYCS, DHPS, CBR1 | NTRK1 3589/4885HTR2A 2844/4885HTR2C 2198/4885 |
| US-20080287692-A1 | Synthesis of cyclopentadiene derivatives | CYCS, CYC1, CBR1 | NTRK1 3369/4885HTR2A 2476/4885HTR2C 1056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.