SCHEMBL7124714

SCHEMBL7124714

Cn1c2c(c3ccccc31)-c1ccccc1C2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.45
HTR2A P28223 1/20 0.45
HTR2C P28335 1/20 0.45
KDM4E B2RXH2 4/20 0.44
HSD17B10 Q99714 3/20 0.44
ALOX15 P16050 1/20 0.44
MAPK1 P28482 1/20 0.44
NTRK1 P04629 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
DRD1 P21728 2/20 0.37
DRD3 P35462 2/20 0.37
DRD2 P14416 1/20 0.37
DRD5 P21918 1/20 0.37
ALKBH5 Q6P6C2 1/20 0.36
FTO Q9C0B1 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29371597 1.00 GPR3 (0.45) GPR3HTR2AHTR2CKDM4EHSD17B10
SCHEMBL19159482 0.85 HTR2A (0.47) GPR3HTR2AHTR2CKDM4EHSD17B10
SCHEMBL4489420 0.83 NTRK1 (0.46) GPR3HTR2AHTR2CKDM4EHSD17B10
SCHEMBL2978540 0.83 MEN1 (0.41) HTR2AHTR2CKDM4EHSD17B10MAPK1
SCHEMBL17806770 0.82 CCNB2 (0.45) HTR2AHTR2CKDM4EHSD17B10ALOX15
SCHEMBL13600300 0.80 HTR2A (0.43) GPR3HTR2AHTR2CKDM4EHSD17B10
SCHEMBL17914705 0.80 NPC1 (0.39) HTR2CKDM4EHSD17B10MAPK1CYP1A2
SCHEMBL23939875 0.79 PGR (0.38) KDM4EHSD17B10MAPK1DRD1DRD3
SCHEMBL4373938 0.79 DRD2 (0.59) KDM4EHSD17B10MAPK1NTRK1CYP1A2
SCHEMBL7130872 0.79 PGR (0.37) HTR2AHTR2CKDM4EHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030148877-A1 Metallocenes and catalysts for olefin-polymerisation BASELL TECHNOLOGY COMPANY BV (NL) 2003-08-07 US claimed
EP-0952978-B1 METALLOCENES AND CATALYSTS FOR OLEFIN-POLYMERISATION BASELL POLYOLEFINE GMBH (DE) 2003-01-22 EP claimed
US-6451724-B1 BIS(N-METHYL-5,10-DIHYDROINDENO(1,2-B)INDOL-10 -YL)TITANIUM DICHLORIDE BASELL TECHNOLOGY COMPANY BV (NL) 2002-09-17 US claimed
US-20240026053-A1 TRANSPARENT ARTICLE POLYPLASTICS CO., LTD. (JP) 2024-01-25 US disclosed
US-11795256-B2 Production method for cyclic olefin copolymer and catalyst composition for copolymerization of norbornene monomer and ethylene POLYPLASTICS CO., LTD. (JP) 2023-10-24 US disclosed
US-11793073-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-17 US disclosed
US-20230312786-A1 PRODUCTION METHOD FOR CYCLIC OLEFIN COPOLYMER POLYPLASTICS CO., LTD. (JP) 2023-10-05 US disclosed
US-20230192930-A1 PRODUCTION METHOD FOR CYCLIC OLEFIN COPOLYMER AND CATALYST COMPOSITION FOR COPOLYMERIZATION OF NORBORNENE MONOMER AND ETHYLENE POLYPLASTICS CO., LTD. (JP) 2023-06-22 US disclosed
US-20200062874-A1 METALLOCENE COMPLEX WITH A HETEROATOM-CONTAINING PI-LIGAND AND PREPARATION METHOD THEREFOR, CATALYST SYSTEM CONTAINING THE SAME AND USE THEREOF PETROCHINA COMPANY LIMITED (CN) 2020-02-27 US disclosed
US-20180223009-A1 OLEFIN-BASED POLYMER WITH EXCELLENT PROCESSABILITY LG CHEM, LTD. (KR) 2018-08-09 US disclosed
US-20180223009-A1 OLEFIN-BASED POLYMER WITH EXCELLENT PROCESSABILITY LG CHEM, LTD. (KR) 2018-08-09 US disclosed
US-20080287692-A1 Synthesis of cyclopentadiene derivatives BASELL POLYOLEFINE GMBH (DE) 2008-11-20 US disclosed
US-20080287692-A1 Synthesis of cyclopentadiene derivatives BASELL POLYOLEFINE GMBH (DE) 2008-11-20 US disclosed
US-7253292-B2 Synthesis of cyclopentadiene derivatives BASELL POLYOLEFINE GMBH (DE) 2007-08-07 US disclosed
US-7253292-B2 Synthesis of cyclopentadiene derivatives BASELL POLYOLEFINE GMBH (DE) 2007-08-07 US disclosed
US-20030148877-A1 Metallocenes and catalysts for olefin-polymerisation BASELL TECHNOLOGY COMPANY BV (NL) 2003-08-07 US disclosed
EP-0952978-B1 METALLOCENES AND CATALYSTS FOR OLEFIN-POLYMERISATION BASELL POLYOLEFINE GMBH (DE) 2003-01-22 EP disclosed
US-6451724-B1 BIS(N-METHYL-5,10-DIHYDROINDENO(1,2-B)INDOL-10 -YL)TITANIUM DICHLORIDE BASELL TECHNOLOGY COMPANY BV (NL) 2002-09-17 US disclosed
EP-0952978-A1 METALLOCENES AND CATALYSTS FOR OLEFIN-POLYMERISATION Montell Technology Company bv (NL) 1999-11-03 EP disclosed
WO-1999024446-A1 METALLOCENES AND CATALYSTS FOR OLEFIN-POLYMERISATION MONTELL TECHNOLOGY COMPANY B.V. (NL) 1999-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11793073-B2 Host materials for electroluminescent devices MCM6, MCM2, MCM4 GPR3 4458/4885HTR2A 4480/4885HTR2C 4594/4885
US-20200062874-A1 METALLOCENE COMPLEX WITH A HETEROATOM-CONTAINING PI-LIGAND AND PREPARATION METHOD THEREFOR, CATALYST SYSTEM CONTAINING THE SAME AND USE THEREOF ORC3, ORMDL3, OR51E2 GPR3 919/4885HTR2A 2491/4885HTR2C 1548/4885
US-20030148877-A1 Metallocenes and catalysts for olefin-polymerisation MT-CO1, CPNE4, MT-CO3 GPR3 3696/4885HTR2A 3191/4885HTR2C 2819/4885
US-20080287692-A1 Synthesis of cyclopentadiene derivatives CYCS, CYC1, CBR1 GPR3 1267/4885HTR2A 2476/4885HTR2C 1056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.