Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | HTR3A | P46098 | 3/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7124714 | 0.85 | GPR3 (0.45) | HTR2AHTR2CKDM4EALOX15MAPK1 | |
| SCHEMBL29371597 | 0.85 | GPR3 (0.45) | HTR2AHTR2CKDM4EALOX15MAPK1 | |
| SCHEMBL984 | 0.76 | HTR2A (0.54) | HTR2AHTR2CKDM4EALOX15MAPK1 | |
| SCHEMBL21524303 | 0.73 | MAOA (0.58) | HTR2AHTR2CKDM4EALOX15MAPK1 | |
| SCHEMBL13600300 | 0.72 | HTR2A (0.43) | HTR2AHTR2CKDM4EALOX15MAPK1 | |
| SCHEMBL1122 | 0.72 | ALOX15 (0.59) | HTR2AHTR2CKDM4EALOX15MAPK1 | |
| SCHEMBL1121 | 0.72 | ALOX15 (0.59) | HTR2AHTR2CKDM4EALOX15MAPK1 | |
| SCHEMBL4489420 | 0.72 | NTRK1 (0.46) | HTR2AHTR2CKDM4EALOX15MAPK1 | |
| SCHEMBL3549753 | 0.71 | HTR2A (0.45) | HTR2AHTR2CKDM4EALOX15MAPK1 | |
| SCHEMBL1146660 | 0.70 | HTR2A (0.51) | HTR2AHTR2CKDM4EALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3196187-A1 | NOVEL COMPOUND | Idemitsu Kosan Co., Ltd (JP) | 2017-07-26 | — | — | EP | disclosed |