Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10028797 | 0.92 | PTGS2 (0.39) | PTGS2ALDH1A1TSHRMAPTHPGD | |
| SCHEMBL10028800 | 0.90 | PTGS2 (0.40) | PTGS2ALDH1A1TSHRMAPTHPGD | |
| SCHEMBL10100082 | 0.84 | PTGS2 (0.40) | PTGS2ALDH1A1TSHRMAPTHPGD | |
| SCHEMBL13470065 | 0.84 | PTGS2 (0.40) | PTGS2ALDH1A1TSHRMAPTHPGD | |
| SCHEMBL4495481 | 0.83 | KMT2A (0.46) | ALDH1A1MAPTHPGDALOX15LMNA | |
| SCHEMBL14294471 | 0.78 | CES1 (0.50) | PTGS2ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL18975440 | 0.78 | PTGS2 (0.38) | PTGS2 | |
| SCHEMBL12336838 | 0.78 | MAPT (0.32) | PTGS2ALDH1A1TSHRMAPTHPGD | |
| SCHEMBL19526462 | 0.75 | PTGS2 (0.31) | PTGS2 | |
| SCHEMBL15276718 | 0.75 | MAPT (0.33) | PTGS2ALDH1A1TSHRMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635781-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2009-12-22 | — | — | US | disclosed |
| US-7635781-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2009-12-22 | — | — | US | disclosed |
| US-7635781-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2009-12-22 | — | — | US | disclosed |
| EP-1926738-B1 | SYNTHESIS OF CYCLOPENTADIENEDITHIOPHENE DERIVATIVES | BASELL POLYOLEFINE GMBH (DE) | 2009-12-09 | — | — | EP | disclosed |
| US-20090118522-A1 | Synthesis of Cyclopentadienedithiophene Derivatives | BASELL POLYOLEFINE GMBH (DE) | 2009-05-07 | — | — | US | disclosed |
| US-20090118522-A1 | Synthesis of Cyclopentadienedithiophene Derivatives | BASELL POLYOLEFINE GMBH (DE) | 2009-05-07 | — | — | US | disclosed |
| US-20080287692-A1 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2008-11-20 | — | — | US | disclosed |
| US-20080287692-A1 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2008-11-20 | — | — | US | disclosed |
| US-20080287692-A1 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2008-11-20 | — | — | US | disclosed |
| EP-1387827-B1 | SYNTHESIS OF CYCLOPENTADIENE DERIVATIVES | BASELL POLYOLEFINE GMBH (DE) | 2008-09-24 | — | — | EP | disclosed |
| US-7253292-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2007-08-07 | — | — | US | disclosed |
| US-7253292-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2007-08-07 | — | — | US | disclosed |
| US-7253292-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2007-08-07 | — | — | US | disclosed |
| WO-2007033937-A1 | SYNTHESIS OF CYCLOPENTADIENEDITHIOPHENE DERIVATIVES | BASELL POLYOLEFINE GMBH (DE) | 2007-03-29 | — | — | WO | disclosed |
| US-20040236115-A1 | Synthesis of cyclopentadiene derivatives | EQUISTAR CHEMICALS, LP | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236115-A1 | Synthesis of cyclopentadiene derivatives | CYCS, DHPS, CBR1 | PTGS2 396/4885ALDH1A1 1619/4885TSHR 4645/4885 |
| US-20080287692-A1 | Synthesis of cyclopentadiene derivatives | CYCS, CYC1, CBR1 | PTGS2 188/4885ALDH1A1 1577/4885TSHR 1110/4885 |
| US-20090118522-A1 | Synthesis of Cyclopentadienedithiophene Derivatives | CCNT1, CBR1, TST | PTGS2 323/4885ALDH1A1 476/4885TSHR 1940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.