SCHEMBL10100082

SCHEMBL10100082

Cc1cc2c(s1)-c1sc(C)cc1C2=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.40
ALDH1A1 P00352 8/20 0.36
TSHR P16473 4/20 0.36
MAPT P10636 3/20 0.36
ALOX15 P16050 2/20 0.36
HSD17B10 Q99714 2/20 0.36
HPGD P15428 2/20 0.36
GFER P55789 1/20 0.36
CDK5 Q00535 1/20 0.36
CDK5R1 Q15078 1/20 0.36
ELANE P08246 2/20 0.33
KMT2A Q03164 3/20 0.32
LMNA P02545 2/20 0.32
MAPK1 P28482 2/20 0.32
MEN1 O00255 2/20 0.32
THRB P10828 2/20 0.32
CYP2C19 P33261 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
MAOA P21397 2/20 0.32
MAOB P27338 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13470065 0.95 PTGS2 (0.40) PTGS2ALDH1A1TSHRMAPTALOX15
SCHEMBL10028797 0.92 PTGS2 (0.39) PTGS2ALDH1A1TSHRMAPTALOX15
SCHEMBL10028800 0.90 PTGS2 (0.40) PTGS2ALDH1A1TSHRMAPTALOX15
SCHEMBL4490123 0.84 PTGS2 (0.40) PTGS2ALDH1A1TSHRMAPTALOX15
SCHEMBL14882885 0.84 ALDH1A1 (0.36) PTGS2ALDH1A1TSHRMAPTALOX15
SCHEMBL2618057 0.84 CES1 (0.47) PTGS2ALDH1A1HPGDKMT2AMEN1
SCHEMBL14646326 0.84 CYP2A6 (0.36) PTGS2ALDH1A1TSHRMAPTHPGD
SCHEMBL14887216 0.84 MAPT (0.33) PTGS2ALDH1A1TSHRMAPTALOX15
SCHEMBL16546083 0.83 PTGS2 (0.37) PTGS2ALDH1A1TSHRMAPTALOX15
SCHEMBL14700582 0.80 PTGS2 (0.42) PTGS2ALDH1A1TSHRMAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11778893-B2 Indaceno derivatives as organic semiconductors CLAP CO., LTD. (KR) 2023-10-03 US disclosed
US-20220416167-A1 OSMIUM-CONTAINING CONJUGATED POLYMER AND METHODS THEREOF XIAMEN UNIVERSITY (CN) 2022-12-29 US disclosed
US-20210384434-A1 INDACENO DERIVATIVES AS ORGANIC SEMICONDUCTORS CLAP CO., LTD. (KR) 2021-12-09 US disclosed
WO-2021143690-A1 OSMIUM-CONTAINING CONJUGATED POLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF 厦门大学 2021-07-22 WO disclosed
EP-3551635-B1 THIENO-INDENO-MONOMERS AND POLYMERS BASF SE (DE) 2021-04-28 EP disclosed
EP-3166949-B1 THIENOTHIOPHENE-ISOINDIGO CLAP CO LTD (KR) 2021-02-17 EP disclosed
WO-2020078815-A1 INDACENO DERIVATIVES AS ORGANIC SEMICONDUCTORS BASF SE (DE) 2020-04-23 WO disclosed
EP-3386989-B1 NAPHTHOINDACENODITHIOPHENES AND POLYMERS BASF SE (DE) 2019-10-23 EP disclosed
US-10388881-B2 Sorting of carbon nanotubes BASF SE (DE) 2019-08-20 US disclosed
WO-2018104367-A2 THIENO-INDENO-MONOMERS AND POLYMERS BASF SE (DE) 2018-06-14 WO disclosed
WO-2012146574-A1 SEMICONDUCTOR MATERIALS BASED ON DIKETOPIPERIDINOPIPERIDINE COPOLYMERS BASF SE (DE) 2012-11-01 WO disclosed
WO-2012142460-A1 NAPHTHALENE-DIIMIDE-HETEROCYCLE-NAPHTHALENE DIIMIDE OLIGOMERS AS ORGANIC SEMICONDUCTORS AND TRANSISTORS THEREFROM GEORGIA TECH RESEARCH CORPORATION (US) 2012-10-18 WO disclosed
EP-2495272-A1 POLYMERIC COMPOUND AND ELECTRONIC ELEMENT Sumitomo Chemical Company, Limited (JP) 2012-09-05 EP disclosed
US-20120205593-A1 POLYMERIC COMPOUND AND ELECTRONIC ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-16 US disclosed
US-20120205596-A1 MACROMOLECULAR COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-16 US disclosed
US-20120205593-A1 POLYMERIC COMPOUND AND ELECTRONIC ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-16 US disclosed
US-20120196078-A1 CONJUGATED POLYMER FIBER, PREPARATION AND USE THEREOF SOTZING GREGORY A (US) 2012-08-02 US disclosed
US-8178629-B2 Conjugated polymer fiber, preparation and use thereof UNIVERSITY OF CONNECTICUT (US) 2012-05-15 US disclosed
US-7321012-B2 Method of crosslinking intrinsically conductive polymers or intrinsically conductive polymer precursors and the articles obtained therefrom THE UNIVERSITY OF CONNECTICUT (US) 2008-01-22 US disclosed
US-20070089845-A1 Conjugated polymer fiber, preparation and use thereof UNIVERSITY OF CONNECTICUT 2007-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210384434-A1 INDACENO DERIVATIVES AS ORGANIC SEMICONDUCTORS IPO11, CYP1B1, IDO1 PTGS2 2766/4885ALDH1A1 94/4885TSHR 4716/4885
US-20120205593-A1 POLYMERIC COMPOUND AND ELECTRONIC ELEMENT ARPC2, AXIN2, EMC2 PTGS2 1771/4885ALDH1A1 1268/4885TSHR 3519/4885
US-11778893-B2 Indaceno derivatives as organic semiconductors IPO11, CYP1B1, IDO1 PTGS2 2766/4885ALDH1A1 94/4885TSHR 4716/4885
US-20120205596-A1 MACROMOLECULAR COMPOUND EXOSC4, TRPC6, MRPS22 PTGS2 4243/4885ALDH1A1 3653/4885TSHR 1066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.