Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4501344 | 0.86 | OPRM1 (0.51) | OPRM1SIGMAR1ACHEMEN1KMT2A | |
| SCHEMBL4036556 | 0.85 | KCNH2 (0.58) | OPRM1HTR2BSIGMAR1GAAMAPT | |
| SCHEMBL4499874 | 0.84 | DCPS (0.45) | OPRM1SIGMAR1ACHEMEN1KMT2A | |
| SCHEMBL4503813 | 0.81 | PARP1 (0.54) | SIGMAR1MEN1KMT2ACCR3 | |
| SCHEMBL4502368 | 0.79 | OPRM1 (0.40) | OPRM1SIGMAR1ACHEMAPTMEN1 | |
| SCHEMBL4502362 | 0.77 | CACNA1G (0.45) | OPRM1SIGMAR1MAPTMEN1KMT2A | |
| SCHEMBL4516525 | 0.77 | TP53 (0.49) | OPRM1SIGMAR1MAPTMEN1KMT2A | |
| SCHEMBL12658352 | 0.76 | RAB9A (0.67) | GAAGFERMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4503853 | 0.76 | MCHR1 (0.46) | GRIN1GRIN2BACHEGAAMAPT | |
| SCHEMBL6325942 | 0.75 | SIGMAR1 (0.46) | OPRM1HTR2BSIGMAR1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517875-B2 | Piperidine derivatives having CCR3 antagonism | TEIJIN LIMITED (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20070032525-A1 | Piperidine derivatives having ccr3 antagonism | TEIJIN LIMITED, A JAPANESE BODY CORPORATE (JP) | 2007-02-08 | — | — | US | disclosed |
| EP-1502916-A1 | PIPERIDINE DERIVATIVES HAVING CCR3 ANTAGONISM | TEIJIN LIMITED (JP) | 2005-02-02 | — | — | EP | disclosed |
| EP-0857718-B1 | ENDOTHELIN ANTAGONIST | SUCAMPO AG (CH) | 2002-08-14 | — | — | EP | disclosed |
| EP-0857718-A1 | ENDOTHELIN ANTAGONIST | R-Tech Ueno, Ltd. (JP) | 1998-08-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032525-A1 | Piperidine derivatives having ccr3 antagonism | CCR3, CCR1, CCR4 | OPRM1 388/4885GRIN1 1258/4885GRIN2B 2189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.