Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278917 | 1.00 | DNM1 (0.54) | DNM1THRBTSHRLMNAMEN1 | |
| SCHEMBL2851674 | 1.00 | DNM1 (0.54) | DNM1THRBTSHRLMNAMEN1 | |
| SCHEMBL5164172 | 1.00 | DNM1 (0.54) | DNM1THRBTSHRLMNAMEN1 | |
| SCHEMBL4486444 | 1.00 | DNM1 (0.54) | DNM1THRBTSHRLMNAMEN1 | |
| SCHEMBL4505356 | 1.00 | DNM1 (0.54) | DNM1THRBTSHRLMNAMEN1 | |
| SCHEMBL23561835 | 1.00 | DNM1 (0.54) | DNM1THRBTSHRLMNAMEN1 | |
| SCHEMBL81499 | 1.00 | DNM1 (0.54) | DNM1THRBTSHRLMNAMEN1 | |
| SCHEMBL12588828 | 1.00 | DNM1 (0.54) | DNM1THRBTSHRLMNAMEN1 | |
| SCHEMBL7714703 | 1.00 | DNM1 (0.54) | DNM1THRBTSHRLMNAMEN1 | |
| SCHEMBL1101719 | 1.00 | DNM1 (0.54) | DNM1THRBTSHRLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065233-A1 | Process for producing alpha-olefin | KURARAY CO., LTD (JP) | 2003-04-03 | — | — | US | claimed |
| CN-110373271-A | A kind of minimizing technology removing plant wax additive and plant wax | 中国烟草总公司郑州烟草研究院 | 2019-10-25 | — | — | CN | disclosed |
| US-20170342033-A1 | Multi-Tyrosine Kinase Inhibitors Derivatives and Methods of Use | ONTOGENESIS LLC (IL) | 2017-11-30 | — | — | US | disclosed |
| US-20170020856-A1 | N-Acylalkyl Prodrugs of Multi-Tyrosine Kinase Inhibitors and Methods of Use | ONTOGENESIS LLC (US) | 2017-01-26 | — | — | US | disclosed |
| EP-1655291-B1 | COMPOUNDS HAVING THROMBOPOIETIN RECEPTOR AGONISM | SHIONOGI & CO (JP) | 2016-08-03 | — | — | EP | disclosed |
| CN-103130739-B | There is the compound of thrombopoietin receptor agonism | SHIONOGI & CO., LTD. (JP) | 2015-09-16 | — | — | CN | disclosed |
| EP-2454233-A2 | SULFONATE SURFACTANTS AND METHODS OF PREPARATION AND USE | Dow Global Technologies LLC (US) | 2012-05-23 | — | — | EP | disclosed |
| US-20090318513-A1 | COMPOUNDS EXHIBITING THROMBOPOIETIN RECEPTOR AGONISM | SHIONOGI & CO., LTD. | 2009-12-24 | — | — | US | disclosed |
| US-7601746-B2 | Compounds exhibiting thrombopoietin receptor agonism | SHIONOGI & CO., LTD. (JP) | 2009-10-13 | — | — | US | disclosed |
| US-20070043087-A1 | Such as 3-{2,6-difluoro-4-[4,5-dihydro-6-(3,3-dimethylbutyl)naphtho[1,2-d]thiazol-2-ylcabamoyl)phenyl]-2-methylacrylic acid | EDDINGPHARM (HONG KONG) COMPANY LIMITED (CN) | 2007-02-22 | — | — | US | disclosed |
| EP-1655291-A1 | COMPOUNDS HAVING THROMBOPOIETIN RECEPTOR AGONISM | SHIONOGI & CO., LTD. (JP) | 2006-05-10 | — | — | EP | disclosed |
| CN-1172887-C | Process for prodn. of alpha-olefine | 可乐丽股份有限公司 | 2004-10-27 | — | — | CN | disclosed |
| US-20030065233-A1 | Process for producing alpha-olefin | KURARAY CO., LTD (JP) | 2003-04-03 | — | — | US | disclosed |
| CN-1397536-A | Process for prodn. of alpha-olefine | KURARAY CO (JP) | 2003-02-19 | — | — | CN | disclosed |
| EP-1277719-A1 | Process for producing alpha-olefin | KURARAY CO., LTD. (JP) | 2003-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318513-A1 | COMPOUNDS EXHIBITING THROMBOPOIETIN RECEPTOR AGONISM | MPL, TEK, GHRHR | DNM1 3781/4885THRB 92/4885TSHR 9/4885 |
| US-20170342033-A1 | Multi-Tyrosine Kinase Inhibitors Derivatives and Methods of Use | ERBB3, PTK2, ERBB2 | DNM1 1315/4885THRB 1482/4885TSHR 1217/4885 |
| US-20070043087-A1 | Such as 3-{2,6-difluoro-4-[4,5-dihydro-6-(3,3-dimethylbutyl)naphtho[1,2-d]thiazol-2-ylcabamoyl)phenyl]-2-methylacrylic acid | DHFR, NAT1, ACR | DNM1 2139/4885THRB 2080/4885TSHR 757/4885 |
| US-20170020856-A1 | N-Acylalkyl Prodrugs of Multi-Tyrosine Kinase Inhibitors and Methods of Use | ERBB3, ERBB2, FLT1 | DNM1 1666/4885THRB 2074/4885TSHR 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.