Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4492284 | 1.00 | DNM1 (0.54) | DNM1THRBTSHRLMNAMEN1 | |
| SCHEMBL2851674 | 1.00 | DNM1 (0.54) | DNM1THRBTSHRLMNAMEN1 | |
| SCHEMBL5164172 | 1.00 | DNM1 (0.54) | DNM1THRBTSHRLMNAMEN1 | |
| SCHEMBL4486444 | 1.00 | DNM1 (0.54) | DNM1THRBTSHRLMNAMEN1 | |
| SCHEMBL4505356 | 1.00 | DNM1 (0.54) | DNM1THRBTSHRLMNAMEN1 | |
| SCHEMBL23561835 | 1.00 | DNM1 (0.54) | DNM1THRBTSHRLMNAMEN1 | |
| SCHEMBL81499 | 1.00 | DNM1 (0.54) | DNM1THRBTSHRLMNAMEN1 | |
| SCHEMBL12588828 | 1.00 | DNM1 (0.54) | DNM1THRBTSHRLMNAMEN1 | |
| SCHEMBL7714703 | 1.00 | DNM1 (0.54) | DNM1THRBTSHRLMNAMEN1 | |
| SCHEMBL1101719 | 1.00 | DNM1 (0.54) | DNM1THRBTSHRLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065233-A1 | Process for producing alpha-olefin | KURARAY CO., LTD (JP) | 2003-04-03 | — | — | US | claimed |
| WO-2020251971-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |
| US-20170295793-A1 | Photodynamic Insecticides | NATIONAL TAIWAN UNIVERSITY (TW) | 2017-10-19 | — | — | US | disclosed |
| US-20170042989-A1 | PHOTOSENSITIZED TRYPANOSOMATIDS AND VACCINE COMPOSITIONS THEREOF | ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE | 2017-02-16 | — | — | US | disclosed |
| EP-1655291-B1 | COMPOUNDS HAVING THROMBOPOIETIN RECEPTOR AGONISM | SHIONOGI & CO (JP) | 2016-08-03 | — | — | EP | disclosed |
| US-9382481-B2 | Polarizing film, display device and production process thereof | FUJIFILM CORPORATION (JP) | 2016-07-05 | — | — | US | disclosed |
| CN-103130739-B | There is the compound of thrombopoietin receptor agonism | SHIONOGI & CO., LTD. (JP) | 2015-09-16 | — | — | CN | disclosed |
| US-20130070899-A1 | POLARIZING FILM, DISPLAY DEVICE AND PRODUCTION PROCESS THEREOF | FUJIFILM CORPORATION (JP) | 2013-03-21 | — | — | US | disclosed |
| US-8133984-B2 | Oligonucleotides comprising signalling pairs and hydrophobic nucleotides, stemless beacons, for detection of nucleic acids, methylation status and mutants of nucleic acids | PENTABASE APS (DK) | 2012-03-13 | — | — | US | disclosed |
| US-8133984-B2 | Oligonucleotides comprising signalling pairs and hydrophobic nucleotides, stemless beacons, for detection of nucleic acids, methylation status and mutants of nucleic acids | PENTABASE APS (DK) | 2012-03-13 | — | — | US | disclosed |
| US-20100068704-A1 | OLIGONUCLEOTIDES COMPRISING SIGNALLING PAIRS AND HYDROPHOBIC NUCLEOTIDES, STEMLESS BEACONS, FOR DETECTION OF NUCLEIC ACIDS, METHYLATION STATUS AND MUTANTS OF NUCLEIC ACIDS | PENTABASE APS (DK) | 2010-03-18 | — | — | US | disclosed |
| US-20090318513-A1 | COMPOUNDS EXHIBITING THROMBOPOIETIN RECEPTOR AGONISM | SHIONOGI & CO., LTD. | 2009-12-24 | — | — | US | disclosed |
| US-7601746-B2 | Compounds exhibiting thrombopoietin receptor agonism | SHIONOGI & CO., LTD. (JP) | 2009-10-13 | — | — | US | disclosed |
| US-20070043087-A1 | Such as 3-{2,6-difluoro-4-[4,5-dihydro-6-(3,3-dimethylbutyl)naphtho[1,2-d]thiazol-2-ylcabamoyl)phenyl]-2-methylacrylic acid | EDDINGPHARM (HONG KONG) COMPANY LIMITED (CN) | 2007-02-22 | — | — | US | disclosed |
| EP-1655291-A1 | COMPOUNDS HAVING THROMBOPOIETIN RECEPTOR AGONISM | SHIONOGI & CO., LTD. (JP) | 2006-05-10 | — | — | EP | disclosed |
| US-20030065233-A1 | Process for producing alpha-olefin | KURARAY CO., LTD (JP) | 2003-04-03 | — | — | US | disclosed |
| EP-1277719-A1 | Process for producing alpha-olefin | KURARAY CO., LTD. (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-4560410-A | POLYOL AND/OR GLYCOL ETHER | UNION CARBIDE CORPORATION (US) | 1985-12-24 | — | — | US | disclosed |
| EP-0066176-B1 | FOUNTAIN SOLUTIONS SUITABLE FOR USE IN LITHOGRAPHIC OFFSET PRINTING | UNION CARBIDE CORPORATION (US) | 1985-01-09 | — | — | EP | disclosed |
| EP-0066176-A1 | Fountain solutions suitable for use in lithographic offset printing | UNION CARBIDE CORPORATION (US) | 1982-12-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100068704-A1 | OLIGONUCLEOTIDES COMPRISING SIGNALLING PAIRS AND HYDROPHOBIC NUCLEOTIDES, STEMLESS BEACONS, FOR DETECTION OF NUCLEIC ACIDS, METHYLATION STATUS AND MUTANTS OF NUCLEIC ACIDS | DNMT1, DNMT3A, DNMT3L | DNM1 1114/4885THRB 2349/4885TSHR 2241/4885 |
| US-20170295793-A1 | Photodynamic Insecticides | PPOX, DDT, CRY1 | DNM1 1075/4885THRB 3439/4885TSHR 3544/4885 |
| US-20090318513-A1 | COMPOUNDS EXHIBITING THROMBOPOIETIN RECEPTOR AGONISM | MPL, TEK, GHRHR | DNM1 3781/4885THRB 92/4885TSHR 9/4885 |
| US-20170042989-A1 | PHOTOSENSITIZED TRYPANOSOMATIDS AND VACCINE COMPOSITIONS THEREOF | CD47, TAP1, TAP2 | DNM1 3703/4885THRB 3139/4885TSHR 1799/4885 |
| US-20070043087-A1 | Such as 3-{2,6-difluoro-4-[4,5-dihydro-6-(3,3-dimethylbutyl)naphtho[1,2-d]thiazol-2-ylcabamoyl)phenyl]-2-methylacrylic acid | DHFR, NAT1, ACR | DNM1 2139/4885THRB 2080/4885TSHR 757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.