SCHEMBL4492706

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4482389	0.90	CDK2 (0.43)	CSNK1DALDH1A1KDM4EMAPTLMNA
	SCHEMBL4489260	0.85	HPGDS (0.55)	ALDH1A1KDM4EMAPK1MAPTLMNA
	SCHEMBL4490500	0.83	CTNNB1 (0.51)	KDM4EMAPTLMNAHTTHPGDS
	SCHEMBL4501469	0.82	APEX1 (0.49)	CSNK1DMAPK1LMNASMN1; SMN2HTT
	SCHEMBL4487073	0.82	KDM4E (0.53)	ALDH1A1KDM4EMAPTTP53HPGDS
	SCHEMBL4490345	0.81	FABP3 (0.51)	ALDH1A1KDM4EMAPTLMNATP53
	SCHEMBL4500058	0.81	SMN1; SMN2 (0.53)	ALDH1A1MAPK1MAPTLMNASMN1; SMN2
	SCHEMBL4489494	0.81	HIF1A (0.60)	ALDH1A1KDM4EMAPTLMNATP53
	SCHEMBL4482218	0.80	ALDH1A1 (0.46)	CSNK1DALDH1A1KDM4EMAPK1MAPT
	SCHEMBL4487533	0.79	KDM4E (0.45)	ALDH1A1KDM4EMAPTLMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.