Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 14/20 | 0.64 |
| ▸ | ALOX5AP | P20292 | 12/20 | 0.64 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.54 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4493866 | 0.81 | FEN1 (0.53) | FEN1ALOX5APPIK3CDNPBWR1 | |
| SCHEMBL21693446 | 0.80 | FEN1 (0.52) | FEN1ALOX5APMAP4K4 | |
| SCHEMBL2814348 | 0.80 | NPBWR1 (0.53) | FEN1ALOX5APPIK3CDNPBWR1MAP4K4 | |
| SCHEMBL3058654 | 0.79 | FEN1 (0.58) | FEN1ALOX5APPIK3CDPDE3BPDE3A | |
| SCHEMBL15916316 | 0.78 | FEN1 (1.00) | FEN1ALOX5AP | |
| SCHEMBL312533 | 0.78 | NPBWR1 (0.60) | FEN1ALOX5APPIK3CDNPBWR1MAP4K4 | |
| SCHEMBL30600399 | 0.75 | TSHR (0.52) | FEN1ALOX5AP | |
| SCHEMBL1702019 | 0.75 | PIK3CD (0.50) | FEN1ALOX5APPIK3CDPDE3BPDE3A | |
| SCHEMBL30704262 | 0.74 | MAP4K4 (0.62) | PIK3CDNPBWR1MAP4K4 | |
| SCHEMBL28051302 | 0.74 | MAP4K4 (0.62) | PIK3CDNPBWR1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961260-B2 | Nitrogenous compound and color conversion film comprising same | LG CHEM, LTD. (KR) | 2021-03-30 | — | — | US | disclosed |
| US-10858375-B2 | Nitrogenous cyclic compound and color changing film comprising same | LG CHEM, LTD. (KR) | 2020-12-08 | — | — | US | disclosed |
| US-20200331932-A1 | NITROGENOUS COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME | LG CHEM, LTD. (KR) | 2020-10-22 | — | — | US | disclosed |
| US-10711015-B2 | Nitrogen-containing compound and color conversion film comprising same | LG CHEM, LTD. (KR) | 2020-07-14 | — | — | US | disclosed |
| US-20200032138-A1 | NITROGEN-CONTAINING COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME | LG CHEM, LTD. (KR) | 2020-01-30 | — | — | US | disclosed |
| US-8211913-B2 | 5-aryl pyridines as 11-beta inhibitors for the treatment of diabetes | HOFFMANN-LA ROCHE INC. (US) | 2012-07-03 | — | — | US | disclosed |
| US-20090149503-A1 | NEW 5-ARYL PYRIDINES AS 11-BETA INHIBITORS FOR THE TREATMENT OF DIABETES | AMREIN KURT | 2009-06-11 | — | — | US | disclosed |
| US-7528159-B2 | 5-aryl pyridines as 11-beta inhibitors for the treatment of diabetes | HOFFMANN-LA ROCHE INC. (US) | 2009-05-05 | — | — | US | disclosed |
| EP-1789041-B1 | ARYL-PYRIDINE DERIVATIVES AS 11-BETA-HSD1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2008-07-09 | — | — | EP | disclosed |
| EP-1789041-A2 | ARYL-PYRIDINE DERIVATIVES AS 11-BETA-HSD1 INHIBITORS | F. Hoffmann-Roche AG (CH) | 2007-05-30 | — | — | EP | disclosed |
| US-20060025455-A1 | New 5-aryl pyridines as 11-beta inhibitors for the treatment of diabetes | HOFFMANN-LA ROCHE INC. | 2006-02-02 | — | — | US | disclosed |
| WO-2006010546-A2 | ARYL-PYRIDINE DERIVATIVES AS 11-BETA-HSD1 INHIBITORS | F. HOFFMAN-LA ROCHE AG (CH) | 2006-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200032138-A1 | NITROGEN-CONTAINING COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME | MYB, NUDC, BLVRB | FEN1 2230/4885ALOX5AP 2347/4885PIK3CD 3498/4885 |
| US-20200331932-A1 | NITROGENOUS COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME | NUDC, MYB, NOTCH4 | FEN1 1846/4885ALOX5AP 2283/4885PIK3CD 3293/4885 |
| US-10711015-B2 | Nitrogen-containing compound and color conversion film comprising same | MYB, NUDC, BLVRB | FEN1 2230/4885ALOX5AP 2347/4885PIK3CD 3498/4885 |
| US-10961260-B2 | Nitrogenous compound and color conversion film comprising same | NUDC, MYB, NOTCH4 | FEN1 1846/4885ALOX5AP 2283/4885PIK3CD 3293/4885 |
| US-10858375-B2 | Nitrogenous cyclic compound and color changing film comprising same | CRY1, MYB, NUDC | FEN1 1637/4885ALOX5AP 2157/4885PIK3CD 2422/4885 |
| US-20090149503-A1 | NEW 5-ARYL PYRIDINES AS 11-BETA INHIBITORS FOR THE TREATMENT OF DIABETES | GPR119, CYP4B1, SLC5A1 | FEN1 3489/4885ALOX5AP 1045/4885PIK3CD 460/4885 |
| US-20060025455-A1 | New 5-aryl pyridines as 11-beta inhibitors for the treatment of diabetes | GPR119, CYP4B1, SLC5A1 | FEN1 3489/4885ALOX5AP 1045/4885PIK3CD 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.