Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | CES2 | O00748 | 1/20 | 0.66 |
| ▸ | CES1 | P23141 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | THRA | P10827 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11060904 | 0.86 | KMT2A (0.73) | KMT2AMEN1CES2CES1TP53 | |
| SCHEMBL297043 | 0.84 | KMT2A (0.71) | KMT2AMEN1CES2CES1TP53 | |
| SCHEMBL29508878 | 0.84 | KMT2A (0.71) | KMT2AMEN1CES2CES1TP53 | |
| SCHEMBL434822 | 0.83 | KMT2A (0.69) | KMT2AMEN1CES2CES1TP53 | |
| SCHEMBL6959553 | 0.83 | KMT2A (0.69) | KMT2AMEN1CES2CES1TP53 | |
| SCHEMBL13168473 | 0.83 | KMT2A (0.69) | KMT2AMEN1CES2CES1TP53 | |
| SCHEMBL432613 | 0.83 | KMT2A (0.69) | KMT2AMEN1CES2CES1TP53 | |
| Hydrochloric Acid SCHEMBL2045145 | 0.83 | KMT2A (0.69) | KMT2AMEN1CES2CES1TP53 | |
| SCHEMBL10355 | 0.83 | KMT2A (0.69) | KMT2AMEN1CES2CES1TP53 | |
| SCHEMBL29282736 | 0.83 | KMT2A (0.69) | KMT2AMEN1CES2CES1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105820124-A | Synthesizing method for binimetinib | 湖南欧亚生物有限公司 | 2016-08-03 | — | — | CN | claimed |
| CN-110072842-A | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 美国陶氏益农公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-109608443-A | Heterocycleamide as protein modulator | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-04-12 | — | — | CN | disclosed |
| CN-109563081-A | It can be used as the heterocycleamide class of protein modulators | 葛兰素史克知识产权开发有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109071514-A | Heterocyclic amides as protein modulators | 葛兰素史密斯克莱知识产权发展有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-105820124-A | Synthesizing method for binimetinib | 湖南欧亚生物有限公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-103502216-B | As pesticide and acaricidal indole carboxamides and benzimidazole-carboxamide | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-05-04 | — | — | CN | disclosed |
| CN-105209031-A | Novel antiviral agents against HBV infection | UNIV DREXEL | 2015-12-30 | — | — | CN | disclosed |
| CN-102341395-B | 3H-imidazo [4,5-c ] pyridine-6-carboxamides as anti-inflammatory agents | BOEHRINGER INGELHEIM INT | 2014-07-30 | — | — | CN | disclosed |
| CN-103502216-A | Indolecarboxamides and benzimidazolecarboxamides as insecticides and acaricides | BAYER IP GMBH | 2014-01-08 | — | — | CN | disclosed |
| US-7632865-B2 | Thioamides and salts thereof and cytokine production inhibitors containing both | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-12-15 | — | — | US | disclosed |
| US-20070219215-A1 | Thioamides and Salts Thereof and Cytokine Production Inhibitors Containing Both | ISHIHARA SANGYO KAISHA, LTD (JP) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219215-A1 | Thioamides and Salts Thereof and Cytokine Production Inhibitors Containing Both | IFNG, TST, STAT6 | KMT2A 1074/4885MEN1 4167/4885CES2 2324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.