Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.71 |
| ▸ | MMP2 | P08253 | 2/20 | 0.71 |
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | MMP1 | P03956 | 1/20 | 0.71 |
| ▸ | MMP9 | P14780 | 1/20 | 0.71 |
| ▸ | MMP8 | P22894 | 1/20 | 0.71 |
| ▸ | MMP13 | P45452 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | CA5A | P35218 | 1/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | F2 | P00734 | 3/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.60 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.60 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | DDX3X | O00571 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13590904 | 0.86 | CA2 (0.75) | CA2MMP2CA1MMP1MMP9 | |
| SCHEMBL1700168 | 0.83 | CA2 (0.71) | CA2MMP2CA1MMP1MMP9 | |
| SCHEMBL2956545 | 0.83 | CA2 (0.71) | CA2MMP2CA1MMP1MMP9 | |
| SCHEMBL12000920 | 0.83 | CA2 (1.00) | CA2MMP2CA1MMP1MMP9 | |
| SCHEMBL922350 | 0.83 | CA2 (0.71) | CA2MMP2CA1MMP1MMP9 | |
| SCHEMBL205255 | 0.82 | KMT2A (0.75) | CA2MMP2CA1MMP1MMP9 | |
| Hydrochloric Acid SCHEMBL15619039 | 0.81 | CA2 (0.69) | CA2MMP2CA1MMP1MMP9 | |
| Dinsed SCHEMBL1814194 | 0.81 | KMT2A (1.00) | CA2MMP2CA1MMP1MMP9 | |
| SCHEMBL58443 | 0.80 | KMT2A (0.72) | CA2MMP2CA1MMP1MMP9 | |
| SCHEMBL1701616 | 0.80 | CA2 (0.67) | CA2MMP2CA1MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115484933-A | Hot melt extrusion solid dispersions containing BCL2 inhibitors | 广州麓鹏制药有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-109641897-A | Bcl-2 selective depressant and its preparation and use | 北京赛林泰医药技术有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-104086540-A | Preparation method for 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS | ANADYS PHARMACEUTICALS INC | 2014-10-08 | — | — | CN | disclosed |
| CN-101677563-B | 5, 6-dihydro-1H-pyridin-2-one compounds | ANADYS PHARMACEUTICALS INC | 2014-06-25 | — | — | CN | disclosed |
| US-7632865-B2 | Thioamides and salts thereof and cytokine production inhibitors containing both | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-12-15 | — | — | US | disclosed |
| US-20070219215-A1 | Thioamides and Salts Thereof and Cytokine Production Inhibitors Containing Both | ISHIHARA SANGYO KAISHA, LTD (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-0791004-A1 | ACYLATED BENZYLGLYCOSIDES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996014325-A1 | ACYLATED BENZYLGLYCOSIDES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219215-A1 | Thioamides and Salts Thereof and Cytokine Production Inhibitors Containing Both | IFNG, TST, STAT6 | CA2 413/4885MMP2 2973/4885CA1 1811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.