Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450135 | 0.84 | KDM4E (0.30) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL4450134 | 0.84 | KDM4E (0.30) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL4450130 | 0.84 | KDM4E (0.30) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| Isoquinoline SCHEMBL16972854 | 0.82 | TNF (0.30) | — | |
| SCHEMBL209689 | 0.77 | TRPA1 (0.34) | TRPA1 | |
| SCHEMBL23400 | 0.77 | KDM4E (0.35) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7098395 | 0.67 | MAPT (0.38) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL17164340 | 0.66 | — | — | |
| SCHEMBL17164341 | 0.66 | — | — | |
| SCHEMBL17164339 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 442 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024102758-A2 | N-(N-AMINOALKYL)PHENANTHRIDIUNIUM SERIES OF CHLORIDE-SENSITIVE FLUOROPHORES AND METHODS OF USE THEREOF | THE GENERAL HOSPITAL CORPORATION (US) | 2024-05-16 | — | — | WO | claimed |
| EP-1852420-B1 | Indole compounds for treating respiratory disorders | ONO PHARMACEUTICAL CO (JP) | 2012-10-17 | — | — | EP | claimed |
| US-8153625-B2 | Nitrogen-containing heterocyclic compounds and medicinal use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2012-04-10 | — | — | US | claimed |
| US-7759336-B2 | Nitrogen-containing heterocyclic compounds and medicinal use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-07-20 | — | — | US | claimed |
| US-12600730-B2 | Substituted cyclopenta[c]pyrroles as ABHD6 antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2026-04-14 | — | — | US | disclosed |
| US-20260083735-A1 | ABHD6 ANTAGONIST | ONO PHARMACEUTICAL CO., LTD. (JP) | 2026-03-26 | — | — | US | disclosed |
| EP-4596555-A1 | ABHD6 ANTAGONIST | ONO Pharmaceutical Co., Ltd. (JP) | 2025-08-06 | — | — | EP | disclosed |
| CN-114605350-B | Polymerizable compound, polymerizable composition containing same, and optically anisotropic body | 江苏创拓新材料有限公司 | 2024-09-13 | — | — | CN | disclosed |
| US-20240270755-A1 | SUBSTITUTED CYCLOPENTA[c]PYRROLES AS ABHD6 ANTAGONISTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2024-08-15 | — | — | US | disclosed |
| WO-2024102758-A2 | N-(N-AMINOALKYL)PHENANTHRIDIUNIUM SERIES OF CHLORIDE-SENSITIVE FLUOROPHORES AND METHODS OF USE THEREOF | THE GENERAL HOSPITAL CORPORATION (US) | 2024-05-16 | — | — | WO | disclosed |
| US-11981682-B2 | Substituted cyclopenta[c]pyrroles as ABHD6 antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2024-05-14 | — | — | US | disclosed |
| WO-2024071398-A1 | ABHD6 ANTAGONIST | 小野薬品工業株式会社 | 2024-04-04 | — | — | WO | disclosed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |
| WO-1998046590-A1 | THERMOGENIC COMPOSITION AND BENZAZEPINE THERMOGENICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-22 | — | — | WO | disclosed |
| EP-0567090-A2 | Benzoxazepine derivatives as cholinesterase inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-27 | — | — | EP | disclosed |
| US-4062852-A | CNS STIMULANTS | E. R. SQUIBB & SONS, INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-4062852-A | CNS STIMULANTS | E. R. SQUIBB & SONS, INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-4003905-A | Diels-alder adducts of benzdiazepines | E. R. SQUIBB & SONS, INC. (US) | 1977-01-18 | — | — | US | disclosed |
| US-3946025-A | MUSCLE RELAXANTS | E. R. SQUIBB & SONS, INC. (US) | 1976-03-23 | — | — | US | disclosed |
| US-3886158-A | 6H-pyrimido{8 1,2-c{9 {8 1,3,5{9 {0 benzoxadiazepines | SQUIBB & SONS INC | 1975-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240270755-A1 | SUBSTITUTED CYCLOPENTA[c]PYRROLES AS ABHD6 ANTAGONISTS | ABHD6, ABHD16A, PITHD1 | KDM4E 1018/4885MEN1 4379/4885ALDH1A1 1199/4885 |
| US-11981682-B2 | Substituted cyclopenta[c]pyrroles as ABHD6 antagonists | ABHD6, ABHD16A, PITHD1 | KDM4E 1038/4885MEN1 4364/4885ALDH1A1 1190/4885 |
| US-12600730-B2 | Substituted cyclopenta[c]pyrroles as ABHD6 antagonists | ABHD6, ABHD16A, HDHD5 | KDM4E 1505/4885MEN1 4611/4885ALDH1A1 548/4885 |
| US-20260083735-A1 | ABHD6 ANTAGONIST | ABHD6, ABHD16A, ABHD12 | KDM4E 2124/4885MEN1 4097/4885ALDH1A1 898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.